Simultaneous Measurement of Local Cortical Blood Flow and Tissue Oxygen Saturation by Near Infra-Red Laser Doppler Flowmetry and Remission Spectroscopy in the Pig Brain

A Postoperative Analysis of Perfusion Dynamics in Deep Inferior Epigastric Perforator Flap Breast Reconstruction

“…The measurement device, O 2 C (Oxygen to See; LEA Medizintechnik, GieQen, Germany), was already validated by Walter et al in an experimental works on 9 anesthetized young pigs. 3 It represented a very good correlation coefficient (r = 0.92). Furthermore, the laser Doppler flowmetry and the microlightguide spectrophotometry are widely used in numerous microvascular studies to evaluate its effectiveness on monitoring flap perfusion and viability.…”

Laparoscopic inguinal herniorrhaphy in babies weighing 5 kg or less

“…The method of the O2C device, light guide tissue spectrophotometry, which combines laser Doppler fluxmetry and tissue spectrometry used for measuring relative blood flow, hemoglobin amount, and hemoglobin oxygenation, has been described in detail elsewhere [15][16][17].…”

Laser Doppler spectroscopy of testes after unilateral orchiopexy

“…The O2C calculates from the absorbed part of the relative hemoglobin amount for the illuminated tissue volume. This measurement represents the hemoglobin amount per tissue volume and is independent of the vessel density, vessel lumen level, and hemoglobin quantity in the blood [13,14].…”

“…Reference values in the healthy controls are between 10 and 50 AU on the arm or leg. Values below 5 are thought to be problematic [14].…”