Simultaneous Measurement of the Calf Blood Flow by Strain-Gauge Plethysmography and the Calf Muscle Blood Flow Measured by¹³³Xenon Clearance

Abstract

TONNESEN, K. H. Simultaneous Measurement of the Calf Blood Flow by Strain-Gauge Plethysmography and the Calf Muscle Blood Flow Measured by 133Xenon Clearance. Scand. J. elin. Lab. Invest. 21, 65-76, 1968.lS3Xenon clearance technique as a measure of the blood flow per unit weight of muscle tissue has been compared to venous occlusion plethysmography in the calf of normal subjects. The comparison was made during reactive hyperemia and in the post-exercise period. In the first mentioned experiments, no agreement between the results by the two methods was obtained.In the experiments in the post-exercise period a highly significant correlation between the two methods was found in each experiment. The mean value of the muscle blood flow, calculated from 133Xenon clearance from sixexperiments, averages 1 13 per cent of the flow, measured simultaneously by plethysmography. The standard deviation in the 6 experiments was calculated to 63 per cent. The major part of this deviation is ascribed to the difficulty of such a comparison.Parallel to this investigation. a re-study of the Scand J Clin Lab Invest Downloaded from informahealthcare.com by University of Sydney on 01/03/15 For personal use only. Scand J Clin Lab Invest Downloaded from informahealthcare.com by University of Sydney on 01/03/15 For personal use only. Scand J Clin Lab Invest Downloaded from informahealthcare.com by University of Sydney on 01/03/15 For personal use only. Scand J Clin Lab Invest Downloaded from informahealthcare.com by University of Sydney on 01/03/15 For personal use only.

Simultaneous 31P-NMR spectroscopy and EMG in exercising and recovering human skeletal muscle: a correlation study

“…This may give problems such as spark formation in capacitors and insufficient RF power. The mean power dissipation (less than 4 mW/g muscle tissue) was far below the values recommended described in the literature (41), and we considered it harmless because of the high diffusion in skeletal muscle (42).…”

Effects of Rehabilitation in Patients with Cardiac Disease

“…A mean difference of 0.14 ml/100ml/min was found between the two series of measurements, with a coefficient of repeatability of 0.17 ml/lOOm1!min. This was much less than the 20% inter-tester error found by Tonnesen (1968).…”

“…The variability in venous occlusion plethysmography is considered to be influenced by physiologic change, variation in technique and systematic error in calculating blood flow from the chart traces (Altenkirch et al 1990;Corbally and Brennan 1990;LeJemtel et al 1992;Tonnesen 1968) Values of 15-25% generally have been found for the coefficient of variation, with higher values in the arm and at rest. The reliability of the model used in our laboratory had previously been determined for both groups of patients using the method described by Bland and Altman (1986).…”

Muscle Blood Flow during Intermittent Exercise: Comparison of the Microdialysis Ethanol Technique and 133Xe Clearance

“…However, criticism has been levied against the '33Xe clearance technique [19, 203. The frequent deviation of the 'j3Xe clearance technique from the microsphere technique and the directly measured blood flow by drop counting has been thoroughly documented [ 19,211. However, as was done in the present study, this deviation can be minimized by using the fast monoexponential portion of the decay curve in calculation of blood flow [22,231 or by using the 'second slope method', as developed by Tonnesen and Sejrsen [l5], to allow time for injection trauma to subside. It is also apparent from the study by Bonde-Petersen et al [24] that the 'j3Xe clearance technique cannot be used in humans to measure very high blood flows.…”