Simultaneous non‐invasive assessment of arterial stiffness and haemodynamics – a validation study

Abstract

The purpose of the study was to estimate the reliability of whole-body impedance cardiography (ICGWB)-derived pulse wave velocity (PWV) and stroke volume index to pulse pressure (SI/PP) measurements. The repeatability and reproducibility of ICGWB parameters were also determined. Agreement between the impedance and Doppler ultrasound-based PWV measurements was estimated in 25 healthy subjects in two consecutive measurements. Impedance-derived SI/PP (SIICG/PP) estimates were compared with simultaneously measured SI/PP based on thermodilution (SITD/PP) and direct Fick (SIFICK/PP) methods in 30 surgical patients. PWV measured between the aortic arch and popliteal artery using the impedance technique with selective electrode configuration (PWVIS) agreed well with the Doppler ultrasound method (PWVDOPP), the bias (PWVDOPP - PWVIS) and precision (+/- SD of differences) being 0.00 and 0.79 m s-1, respectively. PWV derived from the whole-body and popliteal impedance plethysmograms (PWVICG) overestimated slightly PWVDOPP values. The repeatability value for PWVIS was excellent, being 0.54 m s-1. The reproducibility values for PWVDOPP and PWVIS were very similar (2.17 and 2.42 m s-1, respectively). Changes in PWVIS correlated strongly with changes in PWVDOPP (r=0.74; P<0.0001), indicating that both methods reflected the true physiological variation in PWV. The agreement between SIICG/PP and SITD/PP or SIFICK was almost identical to the agreement between the SITD/PP and SIFICK/PP. In conclusion,whole-body impedance cardiography provides handy and reliable means of evaluating arterial stiffness on the basis of PWV and SI/PP simultaneously with conventional haemodynamic parameters. The method is highly repeatable and reproducible.

Increased Cardiac Workload in the Upright Posture in Men: Noninvasive Hemodynamics in Men Versus Women

“…A whole-body impedance cardiography device (CircMon; JR Medical Ltd) that records changes in body electrical impedance during cardiac cycles was used to determine heart rate, stroke volume, and cardiac output. 25,[33][34][35] The description of the method and electrode configuration was reported previously. 25,[33][34][35] The values were normalized to body surface area and expressed as cardiac index, stroke index, systemic vascular resistance index (SVRI), and left cardiac work index (LCWI).…”

“…25,[33][34][35] The description of the method and electrode configuration was reported previously. 25,[33][34][35] The values were normalized to body surface area and expressed as cardiac index, stroke index, systemic vascular resistance index (SVRI), and left cardiac work index (LCWI). SVRI was calculated from the radial BP signal and cardiac index measured by the CircMon device.…”

Interrelationships between indices of longitudinal movement of the common carotid artery wall and the conventional measures of subclinical arteriosclerosis

“…The PWV is determined from the distance and the time difference between the two recording sites. A more detailed description of the method and the validation study has been reported previously (K€ o€ obi et al, 2003;Aatola et al, 2010). Measures of PWV have been found to possess both good repeatability and reproducibility (99% and 87%, respectively) (Tahvanainen et al, 2009).…”

Lower Glomerular Filtration Rate Is Associated With Higher Systemic Vascular Resistance in Patients Without Prevalent Kidney Disease

“…The CircMon device (JR Medical Ltd, Tallinn, Estonia) was used to determine heart rate (HR), stroke index (stroke volume/body surface area), cardiac index (cardiac output/body surface area), systemic vascular resistance index (SVRI), aortic to popliteal pulse wave velocity (PWV), and extracellular fluid volume. [16][17][18][19] The description and repeatability of the method have been published elsewhere. [16][17][18][19] SVRI was calculated from radial tonometric BP and cardiac index measured by the CircMon device.…”

“…[16][17][18][19] The description and repeatability of the method have been published elsewhere. [16][17][18][19] SVRI was calculated from radial tonometric BP and cardiac index measured by the CircMon device. With CircMon, cardiac output shows good agreement with the thermodilution method, 17 while stroke volume shows good correlation with values obtained using 3-dimensional ultrasound.…”