Simultaneous occurrence of keratocystic odontogenic tumor and ameloblastoma in the mandible: A case report

Abstract

Abstract. Keratocystic odontogenic tumors (KCOTs) and ameloblastomas are benign odontogenic tumors that primarily occur in the molar region of the mandible. However, it is uncommon for these tumors to arise simultaneously in a patient's jaw. The present study reported the diagnostic process and features of a rare case of the simultaneous occurrence of KCOT and ameloblastoma in the mandible of a 45-year-old male. Image-based diagnosis was challenging due to several conditions, including the intactness of the teeth and bone cortex as well as the sizes and locations of the lesions. Based on radiographic evidence, the patient was initially misdiagnosed and underwent a biopsy for a radicular cyst and a simple bone cyst prior to the correct diagnoses of KCOT and ameloblastoma, respectively. In addition, the present study discussed the diagnostic process of the present case and reviewed previous literature regarding the simultaneous occurrence of benign tumors of the jaw.

Synchronous Occurrence of Odontogenic Keratocyst and AmeloblastomA: A Case Report and Review of the Literature

“…18 Similarly, the synchronous occurrence of OKC and ameloblastoma in the mandible of a 45 years old male was reported. 19 These two pathologically distinct entities were diagnosed following incisional and excisional biopsies 19 (Table 1). Another reported case demonstrating simultaneous occurrences of odontogenic cysts and/or tumors include cemento-ossifying fibroma and OKC in the mandible, reported by Shimamoto et al 20 Whilst pre-surgical biopsy may have caught the diagnosis of ameloblastoma and changed the surgery performed, there is the possibility it may have been missed in the sample biopsied.…”

A case report of synchronous ameloblastoma and odontogenic keratocyst of the mandible

“…Ameloblastomas are classified as benign odontogenic tumours that are slow-growing and locally infiltrative neoplasms. Ameloblastomas most often involve the mandible (80%) and may have a high recurrence rate, especially when associated with conservative treatment 1 . Ameloblastomas are the most common and clinically significant odontogenic tumours of epithelial origin with significant clinical implications 2 .…”

“…Rare combined odontogenic lesions with histologic evidence of an ameloblastoma and an odontogenic cyst have been reported in the literature 1,9,10 . Unlike our case, the previous cases are ipsilateral, simultaneously occurring lesions or microscopically hybrid lesions.…”