The Crow River, a tributary of the Mississippi River
in Minnesota,
U.S.A., that is impacted by agricultural activities and municipal
wastewater discharges, was sampled approximately monthly at 12 locations
over 18 months to investigate temporal and spatial variations in N-nitrosodimethylamine (NDMA) precursor levels. NDMA precursors
were quantified primarily by measuring NDMA formed under the low chloramine
dose uniform formation conditions protocol (NDMAUFC) and
occasionally using the high dose formation potential protocol (NDMAFP). Raw water NDMAUFC concentrations (2.2 to 128
ng/L) exhibited substantial temporal variation but relatively little
spatial variation. An increase in NDMAUFC was observed
for 126 of 169 water samples after lime-softening treatment. A kinetic
model indicates that under chloramine-limited UFC test conditions,
the increase in NDMAUFC can be attributed to a decrease
in competition between precursors and natural organic matter (NOM)
for chloramines and reduced interactions of precursors with NOM. NDMAUFC concentrations correlated positively with dissolved nitrogen
concentration (ρ = 0.44, p < 0.01) when
excluding the spring snowmelt period and negatively correlated with
dissolved organic carbon concentration (ρ = −0.47, p < 0.01). Overall, NDMA precursor levels were highly
dynamic and strongly affected by lime-softening treatment.