Simultaneous Presentation of Brainstem and Cerebellar Posterior Reversible Encephalopathy Syndrome With Acute Cerebral Infarction

Abstract

Posterior reversible encephalopathy syndrome (PRES) and cerebral infarction are both caused by hypertension, but they rarely occur together. If they do coexist, the selection of a management strategy is difficult because of their pathologic differences. Here, we present an uncommon case of brainstem and cerebellar PRES combined with acute lacunar infarction. For this patient, we used an aggressive blood pressure-lowering regimen during the acute phase of his condition. Once the cerebral edema caused by PRES began to improve, antiplatelet therapy was initiated. The treatment was ultimately successful, and the patient was discharged home. A return to work is now planned. Given the rarity of this combination of conditions and a lack of published evidence for management, our report will contribute to the literature concerning the treatment for this combination of conditions.

Beyond the Diagnosis: Insight Into Posterior Reversible Encephalopathy Syndrome: A Case Series

“…These signs and symptoms may appear hours or days apart, either acutely or subacutely. The characteristic radiographic ndings on MRI of white matter vasogenic edema can appear as hyperintense T2 or hypointense T1 signals mostly involving the parieto-occipital region either symmetrically or asymmetrically [2]. Other regions, such as the frontal and temporal regions, are also involved.…”