The industrial sector often employs piezoelectric materials as actuators for a variety of uses, some of which requires a precise positioning while being limited by space and cost factors that impede the insertion of external position and force sensors. Piezoelectric Actuators are characterized by strong nonlinearities (hysteresis and creep), badly damped oscillations and sensitivity to the environment, especially temperature variation, that make the measurement of the position mandatory to guarantee the required precision and repeatability of piezoelectricbased positioning systems operating at the micro and nanoscale. Self-Sensing Actuation techniques allow the implementation of precise positioning control of Piezoelectric Actuators without the hindrance of external position sensors. This paper reviews the different Self-Sensing Actuation techniques used for precise positioning control of Piezoelectric Actuators. The principle of Self-Sensing Actuation is defined by the capability of deriving the physical state of a Piezoelectric Actuator (displacement, perceived force, ¤ ¤ ¤) without the use of external sensors to directly measure thereof, but rather by estimating it from the measurement of less intrusive and cheaper physical signals produced by the Piezoelectric Actuator itself (throughout current, voltage drop, ¤ ¤ ¤). The applicability and constraints of each Self-Sensing Actuation approach are examined in order to help in the determination of the most adequate approach for precise control of Piezoelectric Actuators positioning and handling force control.