Simultaneous size and luminescence control of NaYF4:Yb3+/RE3+ (RE=Tm, Ho) microcrystals via Li+ doping

Lin, Huang; Xu, Dekang; Teng, Dongdong; Yang, Shenghong; Zhang, Yueli

doi:10.1016/j.optmat.2015.03.044

Cited by 31 publications

(13 citation statements)

References 30 publications

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“…Up to now, crystal lattice modification has been proven to be useful in modulating the upconversion luminescence. − In this work, Ca 2+ ion was chosen as the dopant. Emission intensity of the nanoparticles with 10 mol % dopants showed a three times enhancement than that without Ca 2+ (Figure b).…”

Section: Resultsmentioning

confidence: 99%

Ultrasmall-Superbright Neodymium-Upconversion Nanoparticles via Energy Migration Manipulation and Lattice Modification: 808 nm-Activated Drug Release

Zhang

et al. 2017

ACS Nano

108

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Nd-sensitized upconversion nanoparticles are among the most promising emerging fluorescent nanotransducers. They are activated by 808 nm irradiation, which features merits such as limited tissue overheating and deeper penetration depth, and hence are attractive for diagnostic and therapeutic applications. Recent studies indicate that ultrasmall nanoparticles (<10 nm) are potentially more suitable for clinical application due to their favorable biodistribution and safety profiles. However, upconversion nanoparticles in the sub-10 nm range suffer from poor luminescence due to their ultrasmall size and greater proportion of lattice defects. To reconcile these opposing traits, we adopt a combinatorial strategy of energy migration manipulation and crystal lattice modification, creating ultrasmall-superbright Nd-sensitized nanoparticles with 2 orders of magnitude enhancement in upconversion luminescence. Specifically, we configure a sandwich-type nanostructure with a Yb-enriched intermediate layer [Nd]-[Yb-Yb]-[Yb-Tm] to form a positively reinforced energy migration system, while introducing Ca into the crystal lattice to reduce lattice defects. Furthermore, we apply the nanoparticles to 808 nm light-mediated drug release. The results indicate time-dependent cancer cells killing and better antitumor activities. These ultrasmall-superbright dots have unraveled more opportunities in upconversion photomedicine with the promise of potentially safer and more effective therapy.

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Section: Resultsmentioning

confidence: 99%

Ultrasmall-Superbright Neodymium-Upconversion Nanoparticles via Energy Migration Manipulation and Lattice Modification: 808 nm-Activated Drug Release

Zhang

et al. 2017

ACS Nano

108

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“…NaYF 4 :Yb,Ho and NaYF 4 :Yb,Tm which could expand the absorption spectrum of TiO 2 to NIR region have been reported in previous literatures [14][15][16][17][18][19]. Therefore, the aim of the present work is to formed.…”

Section: Introductionmentioning

confidence: 84%

Fabrication of UCNPs/TiO2 aerogel photocatalyst to improve photocatalytic performance

Li¹,

Kitamoto²

2017

AIP Conference Proceedings

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Abstract. Air and water pollution have become a significant environmental problem all over the world. Recently, an advanced oxidation process emerging to solve these problems has been based on the usage of abundant sunlight for the complete mineralization of toxic pollutants in the air and water. Although TiO 2 semiconductor photocatalysts attract considerable attention owing to its high oxidizing property under ultraviolet (UV) light, the UV light occupies only 5% of solar energy. In the present study, the upconversion nanoparticles of NaYF 4 :Yb,Ho and NaYF 4 :Yb,Tm which convert the near-infrared (NIR) to visible light and UV region are used to combine with anatase TiO 2 aerogel with large specific surface area via a green and easy chemical process.

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“…The amphiphilic polymer DSPE-PEG (2000)-NH 2 was selected as capping ligands to convert the NPs into hydrophilic ones (PEG-NPs). [29][30][31][32] The NPs would become water-dispersible driven by the hydrophobic van der Waals interactions between the hydrophobic tail of the phospholipids and the primary oleate ligands on the NPs surface. The fatty acid chains of the phospholipids are embedded in the hydrophobic surface of the NPs, while the hydrophilic part points out toward the aqueous environment.…”

Section: Targeted Nir Bioimagingmentioning

confidence: 99%

Fe³⁺-codoped ultra-small NaGdF₄:Nd³⁺ nanophosphors: enhanced near-infrared luminescence, reduced particle size and bioimaging applications

Huang

et al. 2019

RSC Adv.

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Simultaneous size and luminescence control of NaYF4:Yb3+/RE3+ (RE=Tm, Ho) microcrystals via Li+ doping

Cited by 31 publications

References 30 publications

Ultrasmall-Superbright Neodymium-Upconversion Nanoparticles via Energy Migration Manipulation and Lattice Modification: 808 nm-Activated Drug Release

Ultrasmall-Superbright Neodymium-Upconversion Nanoparticles via Energy Migration Manipulation and Lattice Modification: 808 nm-Activated Drug Release

Fabrication of UCNPs/TiO2 aerogel photocatalyst to improve photocatalytic performance

Fe³⁺-codoped ultra-small NaGdF₄:Nd³⁺ nanophosphors: enhanced near-infrared luminescence, reduced particle size and bioimaging applications

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Simultaneous size and luminescence control of NaYF4:Yb3+/RE3+ (RE=Tm, Ho) microcrystals via Li+ doping

Cited by 31 publications

References 30 publications

Ultrasmall-Superbright Neodymium-Upconversion Nanoparticles via Energy Migration Manipulation and Lattice Modification: 808 nm-Activated Drug Release

Ultrasmall-Superbright Neodymium-Upconversion Nanoparticles via Energy Migration Manipulation and Lattice Modification: 808 nm-Activated Drug Release

Fabrication of UCNPs/TiO2 aerogel photocatalyst to improve photocatalytic performance

Fe3+-codoped ultra-small NaGdF4:Nd3+ nanophosphors: enhanced near-infrared luminescence, reduced particle size and bioimaging applications

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Fe³⁺-codoped ultra-small NaGdF₄:Nd³⁺ nanophosphors: enhanced near-infrared luminescence, reduced particle size and bioimaging applications