Simultaneous surgery in patients with both cardiac and noncardiac diseases

Yang, Yang; Xiao, Feng; Wang, Jin; Song, Bo; Li, Xihui; Li, Jian; He, Zhisong; Zhang, Huan; Yin, Ling

doi:10.2147/ppa.s100588

Cited by 19 publications

(17 citation statements)

References 30 publications

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“…Thoracic surgeons have been challenged to choose simultaneous surgery or a two-stage approach. 10 Percutaneous coronary intervention (PCI) and CABG are two common cardiac revascularization treatments. The early complications of surgical treatment involving PCI are associated with a significant risk of major intraoperative cardiac ischemia at 6 weeks to 3 months after the stenting.…”

Section: Discussionmentioning

confidence: 99%

Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer

Liu

Wen

et al. 2018

J Int Med Res

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Objective The co-incidence of lung cancer and coronary artery disease (CAD) is increasing in patients of advanced age. This study was performed to demonstrate the efficiency and safety of simultaneous coronary artery bypass grafting and lung cancer surgery in a selected group of older patients. Methods Twenty patients with severe CAD and coexisting lung cancer underwent simultaneous surgical interventions (Group A), and 20 patients with lung cancer underwent an isolated lung cancer operation (Group B). In Group A, the combined operations were carried out through 2 incisions in 3 patients, a single incision in 14 patients, and median sternotomy for heart surgery and thoracoscopic lobectomy for lung cancer in 3 patients. The single-incision approach was used in all patients in Group B. Results The operation time was longer and the blood loss volume was larger in Group A than B. No significant between-group differences were found in the 5-year relapse-free survival rate or 5-year survival rate. Conclusions The simultaneous performance of lung cancer surgery and cardiac surgery was effective and evidently safe in Group A. This treatment approach enabled earlier lung cancer resection and avoidance of the eventual complications associated with further surgical procedures.

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Section: Discussionmentioning

confidence: 99%

Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer

Liu

Wen

et al. 2018

J Int Med Res

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“…However, in China which has a large population, there are few reports of combined esophagectomy and off-pump CABG. By extensively reviewing relevant literature [ 12 , 16 ], we present the largest single-center report in China so far. The simultaneous surgeries may prolong the anesthesia time and surgical time and increase the postoperative heparinization-related bleeding risks.…”

Section: Discussionmentioning

confidence: 99%

Combined surgical treatment of esophageal cancer and coronary heart diseases in elderly patients

et al. 2018

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ObjectiveThe co-incidence of esophageal cancer and coronary heart disease (CHD) is increasing in elderly patients. This study was carried out to analyze the efficiency and safety of simultaneous esophagectomy and cardiac surgery in a selected group of elderly patients.MethodsProspective database for coexistency of severe CHD and esophageal or esophageal-gastric junction cancer was firstly reviewed. Twenty-two patients undergoing combined surgical interventions, including first beating-heart coronary artery bypass grafting (off-pump CABG) and then esophagectomy, were involved as group A. Then, 44 patients undergoing isolated esophagectomy were selected as group B using the propensity score matching method. Data including clinic pathological characteristics and postoperative outcomes were investigated. Kaplan–Meier analysis was used.ResultsThe surgical procedure was performed through left lateral thoracotomy in all patients, except one patient in group A who received median sternotomy and left lateral thoracotomy. The operation time and blood loss were both more in group A, as a result of two operations performed at one session. Patients in both groups were followed up from 1.3 to 78.3 months. No significant between-group was found in overall survival or relapse-free survival.ConclusionThe risk of simultaneous esophagectomy and cardiac surgery is not high. Despite certain differences in clinical indicators between groups, the safety of simultaneous procedures in group A is evident.Trial registrationChiCTR 1800014498. Registered 17 January 2018Electronic supplementary materialThe online version of this article (10.1186/s12957-018-1512-5) contains supplementary material, which is available to authorized users.

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“…However, the presence of CHD increases the surgical morbidity of patients with lung cancer [ 7 ]. This fact creates a clinical dilemma for surgeons on how to decide on the best treatment for with combined early lung cancer and severe CHD, but because surgical techniques have continued to improve, it is now possible to conduct combined coronary artery bypass graft (CABG) surgery and lobectomy for lung cancer in a single combined surgical procedure [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Combined Coronary Artery Bypass Graft (CABG) Surgery and Lung Resection for Lung Cancer in Patients More than 50 Years-of-Age

Liu

Chen

et al. 2018

Med Sci Monit

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BackgroundThe co-existence of coronary heart disease (CHD) and lung cancer is increasing in an increasingly aging population. The aim of this study was to evaluate patient outcome from combined off-pump coronary artery bypass graft (CABG) surgery and lung resection in patients more than 50 years-of-age.Material/MethodsA retrospective clinical study of 23 patients with a mean age of 70.2±8.4 years (range, 51–86 years) included 18 men and five women with CHD and lung cancer who underwent a single operation with combined off-pump CABG surgery and lung resection, for non-small cell lung cancer (NSCLC) (n=22) and small cell lung cancer (n=1). Surgical approaches included: median sternotomy in six patients; left lateral thoracotomy in nine patients; a median sternotomy in three patients; median sternotomy combined with thoracoscopic lobectomy in five patients.ResultsIn the retrospective study of 23 patients, there were no deaths and no new cases of myocardial infarction (MI) in the immediate perioperative period. During the follow-up period, six patients died from lung cancer metastasis or recurrence; one patient died of acute renal failure; and one patient died from the effects of chemotherapy. The remaining 15 patients underwent postoperative follow-up for between 3–79 months with no deaths and no new cases of MI.ConclusionsFor patients who are more than 50 years-of-age and who have CHD and lung cancer, a single combined operation that includes off-pump CABG and lung resection can be safe and effective.

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Simultaneous surgery in patients with both cardiac and noncardiac diseases

Cited by 19 publications

References 30 publications

Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer

Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer

Combined surgical treatment of esophageal cancer and coronary heart diseases in elderly patients

Combined Coronary Artery Bypass Graft (CABG) Surgery and Lung Resection for Lung Cancer in Patients More than 50 Years-of-Age

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