AbstraetAsleep samples had more slow (0.8-3.0 cps) and less fast (13-32 cps) activity than low voltage awake samples. Abundance of intermediate frequencies (1.4-6.0 cps) was higher in frontal-precentral than parietal-occipital EEGs; this is consistent with greater neural maturation of precentral gyrus (Conel, 1939). Present results suggest possible quantitative indices of activation level and neural maturation for behavioral studies.
ProblemQuantitative studies of the energy spectrum in human neonatal EEGs are few; apparently none have employed electronic frequency analysis together with statistical evaluation to study changes in the energy spectrum as a function of electrode location and sleep-wakefulness. Such data may aid relating EEGs to differential maturation of underlying neural structures, and provide quantitative indices of cortical maturation and general excitatory state for behavioral studies.Per cent times of various frequencies have been estimated from intervals between baseline crossings (Bartoshuk & Tennant, 1964). Results showed reliably more slow activity (0.3-2.0 cps) in asleep than awake samples, and higher percentages of intermediate frequencies (1.4-8.3 cps) in frontal-precentral (FPc) than parietal-occipital (PO) tracings.In this study, the more rigorous method of electronic frequency analysis (Walter, 1963) was used to investigate differences between awake and asleep samples, and between FPc and PO tracings.
MethodSs were 17 full-term human newborns at the Providence Lying In Hospital. Median age was 85 hr.Electrode placements were identical with those described earlier (Bartoshuk & Tennant, 1964). Bipolar tracings were recorded on a Grass Model 6 EEG at a sensitivity of 50 microvolts per cm and a time constant of 0.12; the high frequency response was down 20% at 70 cps. These EEGs were recorded on FM tape with an Ampex SP-300 at a tape speed of 3.75 ips. Continuous recordings were also taken of the EKG and stabilimeter activity. Fifty-second samples for frequency analysis were selected from artifact-free segments of the EEG at times when no movements could be observed on the stabilimeter record. A special anterior lead provided a tracing which permitted exclusion of eye movements and blinks. Criteria for selecting awake and asleep samples were those used in the earlier study (Bartoshuk & Tennant, 1964) which provides illustrative primary tracings from 12 Ss. The 17 Ss had acceptable samples of sleep but only 14 had acceptable samples of wakeful-l\yclwn.