Simvastatin Significantly Reduced Alcohol-Induced Cardiac Damage in Adolescent Mice
Makgotso Nchodu,
Alice Efuntayo,
Robin du Preez
et al.
Abstract:Alcohol abuse by adolescents is becoming a serious health concern as they often progress to becoming alcoholics later in life which may lead to heart problems. Chronic alcohol use alters the cardiac function and structure, such as haemodynamic changes, weakening and loss of cardiomyocytes, myocardial fibrosis, and inflammation. Simvastatin is a commonly used drug for the treatment and management of various cardiovascular problems but information on its protective effects against alcohol-induced cardiomyocyte h… Show more
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