Síndrome de Lemierre: Una entidad clínica casi en el olvido. Reporte de tres casos y revisión de la literatura

Sch, Ignacio Maldonado; C, José M Gutiérrez; R, Anita Wilkens; R, Carolina Weitz; A, Alberto Rojas; U, Cristián Varela

doi:10.4067/s0717-93082015000100008

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…Ante la sospecha de trombosis de la vena yugular interna, la ecografía Doppler cervical es el estudio de primera línea con una sensibilidad y especificidad de 92 % y 98 %, respectivamente. La ausencia de flujo al Doppler color y la falta de compresibilidad de la vena representan hallazgos de alta sensibilidad, mientras que el signo más específico es la visualización del trombo (10,11).…”

Section: Discussionunclassified

Síndrome de Lemierre simulando síndrome paraneoplásico: reporte de un caso y revisión de la literatura

Oro

Bermúdez

Durán

et al. 2020

Acta otorrinolaringol cir cabeza cuello

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El síndrome de Lemierre es una enfermedad rara, ocasionada por la complicación grave de una infección orofaringea que se manifiesta con una tromboflebitis séptica en yugular interna y embolización séptica a distancia. Cursa al inicio con fiebre, dolor en área del ángulo de mandíbula, inflamación de región periamigdalina y crecimiento unilateral del cuello luego de una infección en estructuras de cabeza y cuello. Se presenta caso de mujer de 45 años quien consultó por complicación infecciosa posterior a realización de exodoncia. El diagnóstico clínico se realizó en base a los signos y síntomas que indicaban tromboflebitis séptica del seno cavernoso. Se realiza antibióticoterapia con resultados positivos en paciente y mejoría total del estado de salud. Se presenta este caso por lo infrecuente de la entidad.

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Section: Discussionunclassified

Síndrome de Lemierre simulando síndrome paraneoplásico: reporte de un caso y revisión de la literatura

Oro

Bermúdez

Durán

et al. 2020

Acta otorrinolaringol cir cabeza cuello

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Lemierre's Syndrome: A Lethal Complication of Acute Tonsillitis

Amarnani¹,

Ranjan²

2022

Cureus

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Tonsillitis is a condition involving the infection of the lymphoid tissue of the tonsils. This pathology of the tonsils is frequently reported as a childhood illness in children of school-going age. The leading causative agent which is associated with tonsillitis is Group A and B Haemolytic Streptococcus and Staphylococcus and Haemophilus influenzae. With rapid and correct treatment and management with antibiotics and analgesics, it can be resolved, and the patient can be free of the symptoms such as sore throat, dysphagia, pain over the throat, and fever. Though in the minority of cases the diseases can progress and can result in multiple complications which sometimes can be lethal and extremely serious. These can be rheumatic fever, acute glomerulonephritis, or tonsillar cyst. One of the sporadic but equally important and grave syndromes is Lemierre's syndrome, which unfortunately has been labelled as a forgotten disease due to the development of antibiotic therapy and management of the disease. The mortality of the disease was extremely high in the pre-antibiotic era. This disease presents the following findings, such as thrombophlebitis of the internal jugular vein, which usually occurs after the presentation of pharyngeal infection. Which in later stages also gives rise to thrombi that advance and extend throughout the body, in the form of septic emboli. The important microorganism which is isolated and associated with the Lemierre's is Fusobacterium necrophorum, a strict gram-negative anaerobe. This article emphasizes and discusses the pathophysiology, and microbiology of Lemierre's syndrome. It also focuses on the clinical symptoms that include the appropriate and timely diagnosis and treatment of this deadly and fatal syndrome, together with the complications that arise with Lemierre's syndrome as the presenting problem.

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Not always as simple as a UTI: An atypical case of Lemierre's syndrome, the forgotten disease

Panchani

Nair

2021

Clinical Medicine

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A 65-year-old man, who was previously fit and well with no known medical comorbidities, was admitted with symptoms of dysuria, urinary frequency, pyrexia, chills and lethargy. His vitals showed that he was hypotensive, tachycardic and pyrexial. Urine dip was heavily positive for leukocytes and nitrites and had markedly elevated inflammatory markers and mild acute kidney injury. He was commenced on piperacillin/tazobactam. He went on to develop severe left-sided neck swelling and erythema. Ultrasound of the neck with subsequent computed tomography revealed extensive internal jugular vein thrombosis with abscess collection around the vein. Microbiology grew Gram-negative bacilli, later identified as Fusobacterium necrophorum. A diagnosis of Lemierre's syndrome was made. The patient was continued on intravenous piperacillin/tazobactam and metronidazole as per sensitivities and later switched to oral metronidazole. He was initiated on warfarin anticoagulation. He made a remarkable recovery and was discharged with outpatient ear, nose and throat and haematology follow-up.

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Síndrome de Lemierre: Una entidad clínica casi en el olvido. Reporte de tres casos y revisión de la literatura

Cited by 3 publications

References 16 publications

Síndrome de Lemierre simulando síndrome paraneoplásico: reporte de un caso y revisión de la literatura

Síndrome de Lemierre simulando síndrome paraneoplásico: reporte de un caso y revisión de la literatura

Lemierre's Syndrome: A Lethal Complication of Acute Tonsillitis

Not always as simple as a UTI: An atypical case of Lemierre's syndrome, the forgotten disease

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