Sinensetin, rutin, 3′-hydroxy-5, 6, 7, 4′-tetramethoxyflavone and rosmarinic acid contents and antioxidative effect of the skin of apple fruit

Hossain, Mohammad Amzad; Salehuddin, S. M.; Kabir, M. J.; Rahman, Siddiqur; Rupasinghe, H.P. Vasantha

doi:10.1016/j.foodchem.2008.07.085

Cited by 29 publications

(17 citation statements)

References 38 publications

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“…[31][32][33] Chlorogenic acid was the main phenolic compound in quince, apple, and pear fleshes and notably in quince peel 34 and was also the main compound in peaches and nectarines. 35 In 10 peach cultivars, this phenolic acid was found in higher concentration in peels (124.1-294 mg=kg in fresh weight) than in fleshes (40.3-132.1 mg=kg in fresh weight).…”

Section: Resultsmentioning

confidence: 99%

Antioxidant Potential of Peels and Fleshes of Peaches from Different Cultivars

Rossato

Haas²,

Raseira³

et al. 2009

Journal of Medicinal Food

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Increasing recent interest in nutraceuticals and functional foods has led researchers to investigate the antioxidant potential of several fruits. This article evaluates the antioxidant potential and reactivity based on luminol-enhanced chemiluminescence capacity of peach extracts (peels and fleshes) and the contribution of a major compound present in these extracts to antioxidant potential and reactivity. The results obtained showed that the extracts of peels and fleshes of Maciel, Leonense, and Eldorado peach cultivars present free radical scavenging activity in all concentrations tested, with a concentration-dependent action. The immediate inhibition of chemiluminescence and the duration of this inhibition were significantly higher with the extracts than with the major compound (chlorogenic acid) alone, and it can be due to a synergistic or additive effect of other antioxidants present in the extracts. The 50% inhibitory concentration (IC(50)) values for peach extract and chlorogenic acid were 1.19 microg/mL and 8.43 microg/mL, respectively, when total radical-trapping antioxidant potential was evaluated, whereas IC(50) values of 0.41 microg/mL and 1.89 microg/mL was found when total antioxidant reactivity was evaluated in peach extract and chlorogenic acid, respectively. Chlorogenic acid presented a good contribution to antioxidant reactivity and potential, but the fruit extracts provide better antioxidant action. Peach could be of great interest as an important antioxidant source including chlorogenic acid, and it may provide health-promoting advantages to consumers by intake of this fruit or by utilization of its peels as antioxidant sources in industry.

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Section: Resultsmentioning

confidence: 99%

Antioxidant Potential of Peels and Fleshes of Peaches from Different Cultivars

Rossato

Haas²,

Raseira³

et al. 2009

Journal of Medicinal Food

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“…The content of the other important active compound of the plant is known to depend considerably upon extrinsic and intrinsic factors, including soil and climatic conditions, plant ontogenesis phases, harvest and drug storing conditions. Rosmarinic acid is a simple phenolic compound and there are several different analytical methods described in the literature to determine its content in Lamiaceae species, including UV-VIS spectrophotometer, gas chromatography, and HPLC [2], [4]. The simple isocratic method was modified in our work to fit our chromatographic conditions was used to better separate the desired compound.…”

Section: Discussionmentioning

confidence: 99%

“…Its activity especially against rheumatic and inflammatory conditions makes it a sought-after substance for use in phytotherapy. More recently, rosmarinic acid was reported to have anti-HIV activities [4,6,7,9].…”

Section: Orthosiphon Stamineusmentioning

confidence: 99%

Accumulation and variation of rosmarinic acid content in Orthosiphon stamineus Benth. based on phenological stages

Truong¹,

Thu²,

Nghi³

2012

V J Bio

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Orthosiphon Stamineus Benth. (Lamiaceae) is a medicinal herb trusted for many centuries for treating ailments of the kidney, bladder stone, urinary tract infection, liver and bladder problems, diabetes, rheumatism and gout. It is also used to reduce cholesterol and blood pressure. Rosmarinic acid is one of the most important and specific active compound in O. stamineus. The biological effects of rosmarinic acid have been proved. In the research, plant material was harvested at different phenological stages (before budding, full flowering, and after flowering) of the life cycle of the species. The content of rosmarinic acid in samples was measured using HPLC method. Results showed that the accumulation of rosmarinic acid in leaf was higher than that in other organs. The content of rosmarinic acid was increased gradually from before budding stage to flowering stage and reached the maximum content at time of after flowering stage. The content of rosmarinic acid of the 2 nd variety was higher than that of the 1 st variety at the same time (p < 0.05).

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“…1) is a bioactive commonly used for treatments of several health problems especially for kidney stone, diabetes mellitus and gout. It can be isolated from herbs like Orthosiphon stamineus Benth using solvent extraction and chromatographic technique [1]. Akowuah et al has separated sinensetin in the microscale using high performance thin layer chromatography (HPTLC) for quantitative determination [2].…”

Section: Introductionmentioning

confidence: 99%

“…For macroscale separation, especially to produce sinensetin as herb product, solvent extraction method is used [3]. If necessary, it needs special techniques such as sonication [1] or microwave-assisted extraction [4]. The alternative of solvent extraction is the Molecular Imprint Solid Phase Extraction (MISPE) process that uses a specific sorbent material related to the target compound.…”

Section: Introductionmentioning

confidence: 99%