Singapore Neonatal Resuscitation Guidelines 2021

Biswas, Arikta; Ho, Selina Kah Ying; Yip, WY; Kader, Kba; Kong, Jy; Ee, Ktt; Baral, Vijay; Amutha, C.; Quek, BH; Yeo, CL

doi:10.11622/smedj.2021110

Cited by 6 publications

(3 citation statements)

References 164 publications

(177 reference statements)

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“…However, even if the comparison of neonatal complications with healthy newborns is somehow biased, the incidence of complications at birth is estimated as follows: about 10% of term newborns require stimulation to initiate breathing, 5% require positive pressure ventilation before spontaneous breathing, 2% require intubation for longer respiratory support, and 0.1% require cardiac compressions ( 25 , 26 ). About 15% to 20% of newborns require admission in neonatal intensive care units ( 26 , 27 ).…”

Section: Discussionmentioning

confidence: 99%

Neonatal and Early Infancy Features of Patients With Inactivating PTH/PTHrP Signaling Disorders/Pseudohypoparathyroidism

Sindaco

Berkenou

Pagnano

et al. 2023

The Journal of Clinical Endocrinology &Amp; Metabolism

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Background Pseudohypoparathyroidism (PHP) and related disorders newly referred to as inactivating PTH/PTHrP Signaling Disorders (iPPSD) are rare endocrine diseases. Many clinical features including obesity, neurocognitive impairment, brachydactyly, short stature, parathyroid hormone (PTH)-resistance, and resistance to other hormones such as thyroid-stimulating hormone (TSH) have been well described, yet they refer mainly to the full development of the disease during late childhood and adulthood. Objective A significant delay in diagnosis has been reported; therefore, our objective is to increase awareness on neonatal and early infancy presentation of the diseases. To do so, we analyzed a large cohort of iPPSD/PHP patients. Methods We included 136 patients diagnosed with iPPSD/PHP. We retrospectively collected data on birth and investigated the rate of neonatal complications occurring in each iPPSD/PHP category within the first month of life. Results Overall 36% of patients presented at least one neonatal complication, far more than the general population; when considering only the patients with iPPSD2/PHP1A, it reached 47% of the patients. Neonatal hypoglycemia and transient respiratory distress appeared significantly frequent in this latter group, i.e., 10.5% and 18.4%, respectively. The presence of neonatal features was associated with earlier resistance to TSH (p < 0.001) and with the development of neurocognitive impairment (p = 0.02) or constipation (p = 0.04) later in life. Conclusion Our findings suggest that iPPSD/PHP and especially iPPSD2/PHP1A newborns require specific care at birth, because of an increased risk of neonatal complications. These complications may predict a more severe course of the disease, however they are unspecific which likely explains the diagnostic delay.

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Section: Discussionmentioning

confidence: 99%

Neonatal and Early Infancy Features of Patients With Inactivating PTH/PTHrP Signaling Disorders/Pseudohypoparathyroidism

Sindaco

Berkenou

Pagnano

et al. 2023

The Journal of Clinical Endocrinology &Amp; Metabolism

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“…Survival of asphyxiated newborns after resuscitation may be affected by structural factors such as health care professional characteristics (year of experience, and previous training), availability of important equipment in the institution to give care as well as process factors such as the effective implementation of neonatal resuscitation procedure [ 29 , 38 , 39 ].…”

Section: Discussionmentioning

confidence: 99%

Application of Donabedian quality-of-care framework to assess quality of neonatal resuscitation, its outcome, and associated factors among resuscitated newborns at public hospitals of East Wollega zone, Oromia, Western Ethiopia, 2021

Guta

2022

BMC Pediatr

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Background Globally more than 650,000 newborns died on their first day of life from birth asphyxia. The outcome of an asphyxiated newborn depends on the quality of care they received at birth. However, the quality of care newborns received at birth may be below the WHO resuscitation standard. The reason for the poor quality of care is unclear. The Donabedian model, according to the World Health Organization (WHO), is an appropriate framework for health care assessment that focuses on improving the quality of care. So this study aims to assess the quality of neonatal resuscitation, outcome, and its associated factors among newborns with birth asphyxia at public hospitals in the East Wollega zone, 2021. Methods An institution-based cross-sectional study was conducted to observe 410 asphyxiated newborns using consecutive sampling methods. Data was gathered using a pretested structured questionnaire and checklist. Epi-data version 3.1 was used to enter data, which was subsequently exported to Statistical Package for Social Sciences version 25 for analysis. A logistic regression model was employed to determine the variables associated with the outcome variable. The adjusted odds ratio with a 95% confidence interval was calculated, and all variables associated with the outcome variable with a p-value less than 0.05 in multivariable analysis were determined to be significant factors for the outcome of resuscitated newborns. Result A total of 410 asphyxiated newborns were included in this study with a response rate of 97%. From this 87.6% of resuscitated newborns survived. Keeping baby warm [AOR = 6.9; CI (3.1, 15.6)] is associated significantly with increased chances of survival while meconium presence in the airway [AOR = 0.26; CI (0.1, 0.6)], prematurity [AOR = 0.24; CI (0.12, 0.48)], and presence of cord prolapse [AOR = 0.08; CI (0.03, 0.19)] were factors significantly associated with decreased survival of resuscitated newborns at 1 h of life. Conclusion Newborns who were kept warm were more likely to survive compared to their counterparts. While the presence of meconium in the airway, preterm, and cord prolapse was associated with the decreased survival status of newborns. Facilitating referral linkage in the event of cord prolapse, counseling on early antenatal care initiation to decrease adverse outcomes (prematurity), and neonatal resuscitation refresher training is strongly recommended.

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“…Therapeutic hypothermia should be offered to newborns with moderate to severe perinatal asphyxia. (14) In conclusion, we would like to thank our dedicated SRFAC members for their hard work in formulating, reviewing and updating our local resuscitation and first aid guidelines for 2021.…”

Section: Neonatesmentioning

confidence: 99%