Single aortic cross-clamp technique reduces S-100 release after coronary artery surgery

Does Off-pump Coronary Revascularization Reduce the Release of the Cerebral Markers, S-100β and NSE?

“…Dar et al 17 demonstrated that the increased S-100␤ release during and after CPB was significantly higher in patients undergoing CABG employing a single aortic cross-clamping versus patients undergoing partial occluding aortic clamp during the proximal anastomoses construction, suggesting that another mechanism of the increased S-100␤ release could be the intraoperative embolus formation. Such a correlation was previously reported by Babin-Ebell et al 18 , demonstrating a significant relationship between the S-100␤ release and the embolus and thrombin formation, indicating that thrombofibrinous embolism is involved in perioperative brain damage.…”

Is Single or Double Aortic Clamping Safer in Terms of Cerebral Outcome During Coronary Bypass Surgery?

“…Among the strategies developed to minimize aortic clamping/aortic trauma, and thereby prevent neurological complications, is the use of a single clamp technique rather than a double clamp technique requiring use of both an aortic cross clamp and a side-biting clamp. 10,14) Aranki and colleagues reported more favorable outcomes with SCT higher risk patients. 10) Parallel to this study, Dar and coworkers 15) conducted a study with a small sample size (n = 50) and low mean age (59 years).…”

Cardiac Troponin I Concentrations during On-Pump Coronary Artery Surgery

“…On the other cTn-I and Aortic Clamp Technique Capuano hand, Grega and colleagues 17 demonstrated a signifi cant decrease in the relative risk of adverse cerebral outcomes with the use of a single period of clamping (compared to a 2-clamp technique) after primary CABG. Dar and colleagues 18 reported that a single period of clamping improved cerebral protection as measured by the release of S-100 protein.…”