Single-Atom Pt Boosting Electrochemical Nonenzymatic Glucose Sensing on Ni(OH)₂/N-Doped Graphene

Abstract

Conventional nanomaterials in electrochemical nonenzymatic sensing face huge challenge due to their complex size-, surface-, and composition-dependent catalytic properties and low active site density. In this work, we designed a single-atom Pt supported on Ni­(OH)2 nanoplates/nitrogen-doped graphene (Pt1/Ni­(OH)2/NG) as the first example for constructing a single-atom catalyst based electrochemical nonenzymatic glucose sensor. The resulting Pt1/Ni­(OH)2/NG exhibited a low anode peak potential of 0.48 V and high sensitivity of 220.75 μA mM–1 cm–2 toward glucose, which are 45 mV lower and 12 times higher than those of Ni­(OH)2, respectively. The catalyst also showed excellent selectivity for several important interferences, short response time of 4.6 s, and high stability over 4 weeks. Experimental and density functional theory (DFT) calculated results reveal that the improved performance of Pt1/Ni­(OH)2/NG could be attributed to stronger binding strength of glucose on single-atom Pt active centers and their surrounding Ni atoms, combined with fast electron transfer ability by the adding of the highly conductive NG. This research sheds light on the applications of SACs in the field of electrochemical nonenzymatic sensing.

Defective Layered Double Hydroxide Nanosheet Boosts Electrocatalytic Hydrodechlorination Reaction on Supported Palladium Nanoparticles

“…Table S1 shows that the atomic ratio of Ni to Al in Ni x Al 100– x -LDH-OH v can be well controlled by the dose of their precursors, and the x value varies from 52 to 100. The XRD patterns presented in Figure b demonstrate that all of the Ni x Al 100– x -LDH-OH v have the typical layered hydrotalcite structure (PDF#15-0087), except for the Al-free LDH that is indicated to be the β-Ni­(OH) 2 phase (PDF#73-1520) . The TEM images in Figures c and S1 point to the thin nanosheet structures for all of the LDHs, and such a structure is reported to be conducive to the formation of OH v . , The elemental mapping images in Figure d confirm the even distribution of Ni, Al, and O on the sheet.…”

Glucose Biosensors Based on Pinecone-Shaped Au and Ni Nanoparticle Composite Microelectrodes

“…3 What is more, diabetes can induce a variety of chronic complications, such as blindness, coronary heart disease, kidney failure, and others. 1,4,5 Therefore, scientists paid increasing attention to developing accurate, rapid, and reliable measurements of blood glucose for clinical diagnosis and biomedical application.…”

“…Especially, diabetes, caused by high blood glucose, has become a global health problem and more than 463 million people suffer from the disease in the world . What is more, diabetes can induce a variety of chronic complications, such as blindness, coronary heart disease, kidney failure, and others. ,, Therefore, scientists paid increasing attention to developing accurate, rapid, and reliable measurements of blood glucose for clinical diagnosis and biomedical application.…”

Electrochemical quantification of sulfamethoxazole antibiotic in environmental water using zeolitic imidazolate framework (ZIF)-derived single-atom cobalt catalyst in nitrogen-doped carbon nanostructures

“…32 SAC-incorporated carbon material catalysts are widely used in many fields, varying from electrocatalysis (catalysing the reduction of CO 2 and O 2 , evolution of O 2 and H 2 , oxidation of CO, and electrochemical synthesis of NH 3 from N 2 ) [28][29][30]33 to organic synthesis (unsaturated compound hydrogenation and alkene carboboration) 34,35 and biosensing. 36,37 These catalysts have a strong adsorption ability for aromatic compounds because of the strong π-π interactions between the carbon framework and aromatic molecules such as SMX antibiotics.…”

“…hydrogenation and alkene carboboration) 34,35 and biosensing. 36,37 These catalysts have a strong adsorption ability for aromatic compounds because of the strong π-π interactions between the carbon framework and aromatic molecules such as SMX antibiotics.…”