Single cell oil production from low-cost substrates: The possibility and potential of its industrialization

Huang, Chao; Chen, Xue-fang; Xiong, Lian; Chen, Xinde; Ma, Longlong; Chen, Yong

doi:10.1016/j.biotechadv.2012.08.010

Cited by 261 publications

(141 citation statements)

References 175 publications

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“…The main fatty acids in cell were palmitic acid C16:0 and docosahexaenoic acid DHA, C22:6 n-3 which were 34.30 and 44.54 of the total fatty acids, respectively. The fermentation substrate is not the only determinant for industrialization of DHA production, but this factor is undoubtedly the base of DHA production and directly influences the possibility and potential of its industrialization 27 . This declines the use of expensive high quality substrates such as glucose and yeast extract to cultivate DHArich microalgae.…”

Section: Results Of the 15000 L Fermentation Systemmentioning

confidence: 99%

Production of High Docosahexaenoic Acid by <i>Schizochytrium</i> sp. Using Low-cost Raw Materials from Food Industry

2015

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Section: Results Of the 15000 L Fermentation Systemmentioning

confidence: 99%

Production of High Docosahexaenoic Acid by <i>Schizochytrium</i> sp. Using Low-cost Raw Materials from Food Industry

2015

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“…Neutral and non-neutral lipid fractions account for more than 90% and <10% of total lipids, respectively (Huang et al, 2013a). Triglycerides (TAG) and steryl esters (SE) are the major cellular lipids synthesized from sterol, glycerol-3-phosphate, and acyl-CoA.…”

Section: Lipid Accumulation and Degradation In Y Lipolyticamentioning

confidence: 99%

“…The production of cellulosic oil and bioproducts is currently under development. In lignocellulosic feedstock, the ratio of hexoses over pentose sugars is about 1.5-3 to 1, highlighting the importance of pentoses (Huang et al, 2013a). It is notable that the concentration of utilizable sugars in some lignocellulosic feedstock is not adequate for SCO production (Huang et al, 2013a).…”

Section: Challenges In Upgrading the Y Lipolytica Platformmentioning

confidence: 99%

“…FAs can be obtained from plant and microbial resources. Microbial lipids offer several advantages, including faster production, less labor, more flexibility in terms of season and climate, and easier scale-up (Huang et al, 2013a). A microbial platform can be established to convert lignocellulosic sugars or low-value hydrophobic substrates such as waste oils to biofuels, functional lipids, and other value-added bioproducts.…”

Section: Introductionmentioning

confidence: 99%

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Yarrowia lipolytica as an Oleaginous Cell Factory Platform for Production of Fatty Acid-Based Biofuel and Bioproducts

2014

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Today's biotechnologists seek new biocatalysts to meet the growing demand for the bioproducts. This review critically evaluates the potential use of Y. lipolytica as an oleaginous cell factory platform. This yeast has undergone extensive modifications for converting a wide range of hydrophobic and hydrophilic biomass, including alkane, oil, glycerol, and sugars to fatty acid-based products. This article highlights challenges in the development of this platform and provides an overview of strategies to enhance its potential in the sustainable production of biodiesel, functional dietary lipid compounds, and other value-added oleochemical compounds. Future applications of the recombinant Y. lipolytica platform are also discussed.

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“…Various lowcost materials were utilized for microbial oil production. Of these materials, lignocellulosic substrate, that is the most abundant and renewable source in nature, could be a novel and ideal raw substrate for SCO production (Huang et al 2013). Renewable energy sources, such as biodiesel, which are fatty acid methyl esters, have a lot of environmental advantages as they are biodegradable and nontoxic.…”

Section: Introductionmentioning

confidence: 99%

Recycling of lignocellulosic waste materials to produce high-value products: single cell oil and xylitol

Enshaeieh

Abdoli

Madani

et al. 2014

Int. J. Environ. Sci. Technol.

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Application of microorganisms with ability of using environmental wastes such as lignocellulosic materials for converting them to high-value products is important from economical point of view. Valuable products such as single cell oil (SCO) have a high potential to be used in various industrial fields including biodiesel production. Other important products are polyalcohols like xylitol, which are applicable in the food and pharmaceutical industries. In this study, Rhodotorula yeast was isolated from the leaves of Benjamin. Afterward, SCO production was evaluated in a nitrogen-limited medium, and the obtained oil was analyzed by gas chromatography-mass spectrometery. Moreover, xylitol was produced in a media containing xylose and analyzed by high-performance liquid chromatography technique. The yeast strain was identified using polymerase chain reaction method. SCO and xylitol production was also evaluated in a medium containing lignocellulosic materials and other forestry residues. This strain produced SCO and dry biomass of 9.7 and 16.14 g/L, respectively. In addition, in a medium with 140 g/L of xylose, xylitol production was found to be 49.28 g/L. Among waste materials, lipid content of 49 % on grass hydrolysate was found to be incredible. The obtained strain was identified as Rhodotorula mucilaginosa. The results of this study show that by the isolation of yeast with the potential of making use of waste materials, highvalue products can be obtained. Therefore, it can be concluded that the mentioned bioprocess has not only environmental benefits but also is very important from economical view.

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Single cell oil production from low-cost substrates: The possibility and potential of its industrialization

Cited by 261 publications

References 175 publications

Production of High Docosahexaenoic Acid by <i>Schizochytrium</i> sp. Using Low-cost Raw Materials from Food Industry

Production of High Docosahexaenoic Acid by <i>Schizochytrium</i> sp. Using Low-cost Raw Materials from Food Industry

Yarrowia lipolytica as an Oleaginous Cell Factory Platform for Production of Fatty Acid-Based Biofuel and Bioproducts

Recycling of lignocellulosic waste materials to produce high-value products: single cell oil and xylitol

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