Single center experience in patients with unilateral multicystic dysplastic kidney

Moralıoğlu, Serdar; Celayir, Ayşenur Cerrah; Bosnalı, Oktav; Pektaş, Osman Zeki; Bulut, İpek Kaplan

doi:10.1016/j.jpurol.2014.03.008

Cited by 35 publications

(29 citation statements)

References 26 publications

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“…İSÜG'nin gerekirse (USG'de üreter veya renal pelviste genişle-me, ekojenitesinde azalma, kortikal kist varlığı) bu grupta çekilmesini önermektedir (7) . Bazı merkezler her MKDB hastasına rutin İSÜG çekmektedirler (8) . Kuwertz ve ark.…”

Section: Discussionunclassified

“…MKDB tanılı hastalarda İYE oranları %2,5 ile %34,7 olarak bildirilmiştir (2,5,7,8) . Serimizde VUR saptanan bir hastaya 6 ay süreyle antibiyotik profilaksisi uygulanmış, hasta hiç piyelonefrit atağı geçirmemiştir.…”

Section: Discussionunclassified

“…MKDB hastalarında hipertansiyon oranının %0 ile 17,7 arasında görüldüğü bildirilmiştir (8) . Serimizde hiçbir hastada hipertansiyon görülmemiştir.…”

Section: Discussionunclassified

“…Çeşitli çalışmalarda, MKDB'nin 2,5 ile 6,5 yıl arasın-da % 25 ile %52 oranında kaybolduğu rapor edilmiş-tir (4,5,8,11) . Serimizde, ilk 4 yıl içinde kaybolma oranı %46,6 olmuştur.…”

Section: Discussionunclassified

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Tek taraflı multikistik displastik böbrek: Antenatal tanı ve postnatal hasta yönetimi

Ertürk¹

2016

TCCD

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Section: Discussionunclassified

“…MKDB hastalarında hipertansiyon oranının %0 ile 17,7 arasında görüldüğü bildirilmiştir (8) . Serimizde hiçbir hastada hipertansiyon görülmemiştir.…”

Section: Discussionunclassified

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Tek taraflı multikistik displastik böbrek: Antenatal tanı ve postnatal hasta yönetimi

Ertürk¹

2016

TCCD

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“…6 These authors advocate for ongoing followup allowing for early identification of those at risk and timely intervention. [6][7][8][9] Regarding the use of voiding cystourethrograms (VCUGs), the literature suggests some urologists continued to routinely perform them in all children with MCDK until as recently as 2012, 10 with more recent publications advocating for judicious use of VCUG, only being ordered when US shows contralateral anomalies, 3 or only ordering a VCUG if the child has a urinary tract infection, regardless of the presence of mild contralateral hydronephrosis. 11 Though not included in the initial guideline, it has been shown that 15% of children with MCDK have malformations of the ipsilateral internal genitalia, warranting followup.…”

Section: Mcdk In the Neonatementioning

confidence: 99%

Multicystic dysplastic kidney (MCDK) in the neonate: The role of the urologist

Psooy

2016

CUAJ

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Outcome of children with multicystic dysplastic kidney: Does involved side matter?

Yavuz,

Kıyak,

Sander

2023

Birth Defects Research

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BackgroundMulticystic dysplastic kidney (MCDK) is a common anomaly detected on antenatal ultrasound. We aimed to assess the profile of children with MCDK and to investigate whether the involved side has any effect on outcome.MethodsThirty‐nine patients with MCDK and 20 controls were enrolled. Patients who estimated glomerular filtration rate (eGFR) values over 90 mL/min/1.73 m2 were compared with controls. Comparison was made between the involved sides.ResultsMKDB was right‐sided in 20 (51.3%) and left‐sided in 19 (48.7%) patients. 33.3% had additional urinary tract abnormality, 10.2% had systemic abnormality. 82% showed contralateral kidney enlargement. 48.7% involuted, 17.9% underwent nephrectomy. 35.8% suffered from urinary tract infection (UTI). 5.1% had renal scarring (RS). 30% developed microalbuminuria. 12.8% complicated with hypertension. 17.9% progressed to chronic kidney disease (CKD). Hypertension was independent risk factor for developing CKD. Blood pressure, cystatin C and urine microalbumin/creatinine levels were increased, and eGFR values were decreased in patients compared to controls. No significant difference was found between the two sides for rates of involution, UTI, RS, nephrectomy, and additional abnormality. Cystatin C levels were higher on the right than left sides (p = .033).ConclusionChildren with MCDK predispose to renal deterioration even at normal eGFR values. Although cystatin C levels tended to increase in right‐sided patients, the involved side seemed to have no significant effect on renal outcome. Hypertension was main determinant for progression to CKD in MCDK.

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Single center experience in patients with unilateral multicystic dysplastic kidney

Cited by 35 publications

References 26 publications

Tek taraflı multikistik displastik böbrek: Antenatal tanı ve postnatal hasta yönetimi

Tek taraflı multikistik displastik böbrek: Antenatal tanı ve postnatal hasta yönetimi

Multicystic dysplastic kidney (MCDK) in the neonate: The role of the urologist

Outcome of children with multicystic dysplastic kidney: Does involved side matter?

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