Single-Center Experience with Three Metallic Ureteral Stents (Allium<sup>®</sup> URS, Memokath™-051, and Resonance<sup>®</sup>) for Chronic Ureteral Obstruction

Khoo, Christopher C.; Ho, Chun Hok; Palaniappan, Varun; Ting, Andrew; Forster, Luke; Kondjin-Smith, Mitra; Abboudi, Hamid; Hanna, Milad; El‐Husseiny, Tamer; Dasgupta, Ranan

doi:10.1089/end.2021.0208

Cited by 9 publications

(2 citation statements)

References 24 publications

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“…Complications related to MUS placement were observed in our patients, with hematuria and low back pain being the most common. These findings are consistent with previous studies that have reported similar complication rates with MUS 20 , 21 . However, the overall complication rate observed in our study was relatively low, suggesting that MUS are a safe treatment option for ureteral strictures.…”

Section: Discussionsupporting

confidence: 93%

Metal ureteral stents for ureteral stricture: 2 years of experience with 246 cases

Gao,

Di,

Chen

et al. 2023

International Journal of Surgery

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Background: Metal ureteral stents (MUS) has gained popularity as an endoscopic treatment alternative for the management of ureteral strictures. The aim of this study was to evaluate the safety, efficacy, and tolerability of MUS for treating ureteral strictures and to identify any factors that could influence the success of this intervention. Methods: This study is a prospective analysis of the efficacy and safety of MUS for treating ureteral strictures in a single-center setting. The study enrolled 246 patients who had been diagnosed with ureteral strictures and had undergone MUS placement between January 2019 and July 2021. The patients were followed up for a duration of 2 years. Results: The overall success rate of MUS placement was 71.7%. Furthermore, the success rate of ureteral strictures after kidney transplantation (78.2%) was significantly higher than common ureteral strictures (73.0%) or recurrent ureteral strictures (67.6%). Additionally, post-surgery, there was a considerable reduction in hydronephrosis volume (68.9±96.1 vs. 32.1±48.8 cm3), blood creatinine level (103.7±49.8 vs. 94.4±47.5 mol/L) and urea nitrogen level (6.7±7.2 vs. 5.1±2.4 mmol/L). The study also reported that the rate of adverse events associated with MUS was relatively low, included hematuria (7.9%), pain (6.8%), urinary tract infection (6.4%) and lower urinary tract symptoms (5.3%). Conclusion: MUS appear to be a safe and effective treatment option for ureteral strictures, with a high success rate and low complication rate. These results have important implications for the management of ureteral strictures and can help guide clinical decision-making in the selection of treatment options.

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Section: Discussionsupporting

confidence: 93%

Metal ureteral stents for ureteral stricture: 2 years of experience with 246 cases

Gao,

Di,

Chen

et al. 2023

International Journal of Surgery

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“…These benefits may have resulted from the following reasons: first, recurrent UPJO always comes with segmental stenosis, and the large-caliber segmental design of the covered metallic ureteral stent can not only ensure adequate renal urine drainage but also minimize the irritation of the normal segment of ureter wall; second, the segmental covered metallic stent has no double-J structure, hence, that there is only 0.5 to 1 cm soft and elastic tubular end exposed to the internal renal pelvis after the surgery. The new one reduces the irritation to the renal pelvis and bladder urothelial tissue as compared with the traditional double-J stent; third, the indwelling time of the coated metallic ureteral stent is much longer, [ 23 ] which significantly reduces the frequencies of stent replacement and patients’ hospitalization, thereby relieving the psychological, physical, and economic burden from patients.…”

Section: Discussionmentioning

confidence: 99%

Long-term maintenance treatment of recurrent ureteropelvic junction obstruction with covered metallic ureteral stent

Tang

Wang

et al. 2023

Medicine

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Whether or not the covered metallic ureteral stent can be used as maintenance treatment for recurrent ureteropelvic junction obstruction (UPJO) after pyeloplasty is unknown. Therefore, this study aims to analyze its feasibility. We retrospectively analyzed the records of 20 patients with recurrent UPJO who were treated with the covered metallic ureteral stents from March 2019 to June 2021 at our institution. Then, we assessed their renal function, stent patency and stent-related quality of life by the blood creatinine, renal ultrasound (or computed tomography), and the Chinese version of the ureteral symptom score questionnaire (USSQ). The last follow-up mean blood creatinine dropped from 0.98 ± 0.22 to 0.91 ± 0.21 mg/dL ( P = .04), and the median renal pelvic width was reduced from 3.25 (3.10) to 2.00 (1.67) cm ( P = .03) compared with the preoperative conditions. Meanwhile, the last follow-up mean USSQ total score of the covered metallic ureteral stent among the 16 patients with preoperative indwelling double-J ureteral stent was 78.56 ± 14.75, significantly lower than the preoperative USSQ total score, which was 102.25 ± 5.57 ( P < .001). During the median duration of follow-up of 27.00 (18.00) months, 85% (17/20) of patients maintained unobstructed drainage from the renal pelvis to the ureter. Stent-related complications occurred in 7 patients, 3 of which failed because of complications, including stent migration (1 patient), stent encrustation (1 patient), and stent-related infection (1 patient). The covered metallic ureteral stent is feasible for the long-term maintenance treatment of recurrent UPJO after pyeloplasty.

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Urinary Tract Infections and Encrustation in Urinary Stents

et al. 2022

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Regardless clinical benefits of urinary stents, these indispensable tools for everyday practice come with substantial hindrances as they can lead to stent-related symptoms, encrustation, hematuria, infection and hence to an overall reduction in the quality of life of patients. Bacterial colonization of foreign bodies has been a significant problem in Medicine in general and Urology in particular for decades. Studies have shown that around 42–100% of all indwelling ureteral stents are colonized by bacteria. Typically, the bacteria continue to form a more mature biofilm as large, structured communities of bacteria adhere onto surfaces and secret polysaccharides, nucleic acids, lipids and proteins that form an eminently protective cast around the bacteria. Due to the complex biology and interactions between foreign body surfaces, the host and microbes, a simple, one-fits-all solution is not very likely to be developed. Nonetheless, our knowledge of the underlying biology has dramatically expanded, and novel technologies are being tested. Probably the easiest solution is to appraise ureteral stenting critically and omit stenting whenever feasible. However, for patients in need of a ureteral stent the future might bring “ideal” stents that are biodegradable, coated to avoid biofilm formation and incrustation and ideally emit sufficient levels of specific drugs that prevent tissue ingrowth or even dissolve urinary calculi.

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Single-Center Experience with Three Metallic Ureteral Stents (Allium^® URS, Memokath™-051, and Resonance^®) for Chronic Ureteral Obstruction

Cited by 9 publications

References 24 publications

Metal ureteral stents for ureteral stricture: 2 years of experience with 246 cases

Metal ureteral stents for ureteral stricture: 2 years of experience with 246 cases

Long-term maintenance treatment of recurrent ureteropelvic junction obstruction with covered metallic ureteral stent

Urinary Tract Infections and Encrustation in Urinary Stents

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Single-Center Experience with Three Metallic Ureteral Stents (Allium® URS, Memokath™-051, and Resonance®) for Chronic Ureteral Obstruction

Cited by 9 publications

References 24 publications

Metal ureteral stents for ureteral stricture: 2 years of experience with 246 cases

Metal ureteral stents for ureteral stricture: 2 years of experience with 246 cases

Long-term maintenance treatment of recurrent ureteropelvic junction obstruction with covered metallic ureteral stent

Urinary Tract Infections and Encrustation in Urinary Stents

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Product

Resources

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Single-Center Experience with Three Metallic Ureteral Stents (Allium^® URS, Memokath™-051, and Resonance^®) for Chronic Ureteral Obstruction