Single dose antibiotic prophylaxis in high risk patients undergoing transurethral prostatectomy

McEntee, Gerry; McPhail, Sean; Mulvin, D.; Thomson, R

doi:10.1002/bjs.1800740312

Cited by 21 publications

(7 citation statements)

References 7 publications

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“…Thirty‐six studies were included in the final synthesis: one thesis and 35 journal articles . The 36 studies included 11 randomized controlled studies (two crossover designs), 18 cohort studies, one retrospective survey, three pharmacokinetic and three quasiexperimental studies.…”

Section: Resultsmentioning

confidence: 99%

Adverse effects of a single dose of gentamicin in adults: a systematic review

Hayward¹,

Harding²,

Molloy³

et al. 2017

Brit J Clinical Pharma

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RESULTSIn total, 15 522 records were identified. After removal of duplicates, screening of title/abstracts for relevance and independent selection of full texts by two reviewers, 36 studies were included. Across all the included studies, 24 107 participants received a single one-off dose of gentamicin (doses ranged from 1 mg kg -1 to 480 mg per dose). Acute kidney injury was described in 2520 participants receiving gentamicin. The large majority of cases were reversible. There were no cases of ototoxicity reported in patients receiving gentamicin. A meta-analysis was not performed due to study heterogeneity. CONCLUSIONSA significant number of patients saw a transient rise in creatinine after a single dose of gentamicin at doses up to 480 mg. Persistent renal impairment and other adverse events were relatively rare.British Journal of Clinical Pharmacology Br J Clin Pharmacol (2018) 84 223-238 223

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Section: Resultsmentioning

confidence: 99%

Adverse effects of a single dose of gentamicin in adults: a systematic review

Hayward¹,

Harding²,

Molloy³

et al. 2017

Brit J Clinical Pharma

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“…Postoperative UTIs and bacteremia were the typical complications of TUR‐P, so effective AMP is necessary. Many studies on the necessity of AMP for TUR‐P have been reported 3,13,14,46–89 . Among them, many randomized comparative studies and meta‐analysis 88,89 were included.…”

Section: Detailed Expositionmentioning

confidence: 99%

Japanese guidelines for prevention of perioperative infections in urological field

et al. 2007

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For urologists, it is very important to master surgical indications and surgical techniques. On the other hand , the knowledge of the prevention of perioperative infections and the improvement of surgical techniques should always be considered. Although the prevention of perioperative infections in each surgical field is a very important issue, the evidence and the number of guidelines are limited. Among them, the preparation of guidelines has progressed , especially in gastrointestinal surgery. The Center for Disease Control and Prevention (CDC) proposed guidelines for the prevention of surgical site infections, which have been used worldwide. In urology, the original guidelines were different from those of general surgery, due to many endourological procedures and urine exposure in the surgical field. The Japanese Society of UTI Cooperative Study Group has thus framed these guidelines supported by The Japanese Urological Association. The guidelines consist of the following nine techniques: open surgeries, laparoscopic surgeries, transurethral resection of bladder tumor, ureterorenoscope and transurethral lithotripsy, transurethral resection of the prostate, prostate biopsy, cystourethroscope, pediatric surgeries in the urological field , and extracorporeal shock wave lithotripsy and febrile neutropenia. These are the first guidelines for the prevention of perioperative infections in the urological field in Japan. Although most of these guidelines were made using reliable evidence, there are parts without enough evidence. Therefore, if new reliable data is reported , it will be necessary for these guidelines to be revised in the future. Key words:Open surgery, Laparoscopic surgery, TUR, Prostate biopsy, Cystourethroscope, ESWL. I. General remarksUrological practice mainly consists of surgical procedures, since the field of urology is a division of surgery. Therefore, it is very important to master surgical indications and surgical techniques. On the other hand , the knowledge of the prevention of perioperative infections and the improvement of surgical techniques should always be considered. Although the prevention of perioperative infections in each surgical field is a very important issue, these evidences are limited and the number of guidelines is limited. Among them, the preparation of guidelines has progressed , especially in gastrointestinal surgery. The Center for Disease Control and Prevention (CDC) proposed guidelines for the prevention of surgical site infections), 1 which have been used worldwide. In urology, the original guidelines were different from those of general surgery, due to many endourological procedures and urine exposure in the surgical field. We have thus framed these guidelines supported by The Japanese Urological Association. I-I Definition and classification of perioperative infectionsA perioperative infection is defined as an infection that occurs within one month after an operation. These infections are divided into two groups: surgical site infections (SSIs) and remote i...

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“…It is well documented that administration of antimicrobics to these two categories of patients before surgery can reduce the frequency of clinically significant infectious complications, and hence there is general agreement that these patients are candidates for some regimen of antimicrobics in relation to TURP (5, 19,32,34,36,47). However, the first concern should be to avoid urethral catheterization and any other instrumentation whenever possible (7).…”

Section: Risk Factors For Uti In Connection With Turpmentioning

confidence: 99%

Antimicrobial Prophylaxis in Transurethral Resection of the Prostate with Special Reference to Preoperatively Sterile Urine

Christensen

1991

Scandinavian Journal of Urology and Nephrology

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The literature on antimicrobial prophylaxis in connection with transurethral resection of the prostate (TURP) is reviewed, and it is concluded that there is no proof of clinically significant beneficial effect of prophylaxis when the urine is sterile preoperatively. Prophylaxis is indicated when bacteriuria or an indwelling urethral catheter is present at the time of operation. Other possible risk factors, such as diabetes mellitus, neurogenic bladder dysfunction, immunosuppression, earlier coronary bypass operation and the presence of prosthetic devices, need further investigation.

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Single dose antibiotic prophylaxis in high risk patients undergoing transurethral prostatectomy

Cited by 21 publications

References 7 publications

Adverse effects of a single dose of gentamicin in adults: a systematic review

Adverse effects of a single dose of gentamicin in adults: a systematic review

Japanese guidelines for prevention of perioperative infections in urological field

Antimicrobial Prophylaxis in Transurethral Resection of the Prostate with Special Reference to Preoperatively Sterile Urine

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