Single dose intravenous tropisetron in the prevention of post-operative nausea and vomiting following gynaecological surgery: a double-blind, multicentre, dose-comparison study

Capouet, Vincent; Pauw, C. De; Ivens, D.; Ickx, Brigitte; Hulstaert, Frank

doi:10.1097/00003643-199603000-00073

Drugs for preventing postoperative nausea and vomiting

Carlisle

¹

,

Stevenson²

2006

Cochrane Database of Systematic Reviews

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Either nausea or vomiting is reported to affect, at most, 80 out of 100 people after surgery. If all 100 of these people are given one of the listed drugs, about 28 would benefit and 72 would not. Nausea and vomiting are usually less common and, therefore, drugs are less useful. For 100 people, of whom 30 would vomit or feel sick after surgery if given placebo, 10 people would benefit from a drug and 90 would not. Between one to five patients out of every 100 people may experience a mild side effect, such as sedation or headache, when given an antiemetic drug. Collaborative research should focus on determining whether antiemetic drugs cause more severe, probably rare, side effects. Further comparison of the antiemetic effect of one drug versus another is not a research priority.

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Drugs for preventing postoperative nausea and vomiting

Carlisle

¹

,

Stevenson²

2017

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

Either nausea or vomiting is reported to affect, at most, 80 out of 100 people after surgery. If all 100 of these people are given one of the listed drugs, about 28 would benefit and 72 would not. Nausea and vomiting are usually less common and, therefore, drugs are less useful. For 100 people, of whom 30 would vomit or feel sick after surgery if given placebo, 10 people would benefit from a drug and 90 would not. Between one to five patients out of every 100 people may experience a mild side effect, such as sedation or headache, when given an antiemetic drug. Collaborative research should focus on determining whether antiemetic drugs cause more severe, probably rare, side effects. Further comparison of the antiemetic effect of one drug versus another is not a research priority.

show abstract