Single Injection Spinal Anaesthesia With Amethocaine and Morphine for Transuretheral Prostatectomy

Abstract

The intrathecal administration of amethocaine plus morphine as an anaesthetic technique for providing surgical anaesthesia and postoperative analgesia was evaluated in 24 patients undergoing transurethral resection of the prostate. The efficacy of the technique was compared with that observed following spinal anaesthesia with amethocaine alone. Twelve patients (group I) received spinal anaesthesia with amethocaine 12-14 mg and a further 12 patients (group II) received spinal anaesthesia with amethocaine 12-14 mg plus morphine 1 mg. In group II the addition of morphine 1 mg to the amethocaine produced excellent surgical anaesthesia and postoperative analgesia and these patients had significantly less postoperative pain than the patients who received amethocaine alone. There was a high frequency of side-effects associated with intrathecal morphine in group II, for example, subtle respiratory depression, nausea, vomiting and pruritus.

Comparative effects of buprenorphine and dexmedetomidine as adjuvants to bupivacaine spinal anaesthesia in elderly male patients undergoing transurethral resection of prostrate: A randomized prospective study

“…Since the first clinical use of intrathecal morphine in 1979, several studies have shown the benefits of intrathecal opioids as adjuvants to local anesthetics in providing postoperative pain relief. [ 4 5 6 7 8 9 10 11 12 13 14 15 16 17 ] However, redistribution by rostral spread following intrathecal administration results in several adverse effects such as nausea, vomiting and respiratory depression that become limiting factor in the use of intrathecal opioids. [ 18 19 ] Therefore, several spinal adjuvant drugs such as α 2 agonists (clonidine or dexmedetomidine) have been studied as alternatives to intrathecal opioids.…”

Spinal Block Anesthesia With Morphine in a Hemorrhoidectomy

“…Recently, a low dose (0.1-0.25 mg) of intrathecal morphine has been used to reduce the possible complications and side effects of morphine [1]. Spinal anesthesia with such a low dose of morphine has proven to be safe and effective for a hemorrhoidectomy [2], Caesarean section [3], tubal ligation [4], transurethral prostatectomy [5] and orthopedic surgery [6]. The biggest challenge in a hemorrhoidectomy is to control pain after surgery.…”