2017
DOI: 10.1016/j.cancergen.2017.03.006
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Single nucleotide polymorphisms in an Indian cohort and association of CNTN4 , MMP2 and SNTB1 variants with oral cancer

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Cited by 9 publications
(11 citation statements)
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“…Previous studies indicate that SNTB1 is involved in the initiation of autophagy in pancreatic cancer cells and has a protective effect on acute pancreatitis [7]. In addition, it has also been reported that SNTB1 is closely related to the occurrence of oral cancer and is considered to be a susceptibility locus for severe myopia [9,10]. However, the functional roles of SNTB1 in CRC are still unknown.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Previous studies indicate that SNTB1 is involved in the initiation of autophagy in pancreatic cancer cells and has a protective effect on acute pancreatitis [7]. In addition, it has also been reported that SNTB1 is closely related to the occurrence of oral cancer and is considered to be a susceptibility locus for severe myopia [9,10]. However, the functional roles of SNTB1 in CRC are still unknown.…”
Section: Discussionmentioning
confidence: 99%
“…Loss and reduction of SNTB1 is closely associated with Duchenne muscular dystrophy and Becker's muscular dystrophy [6]. The functional variants of SNTB1 can cause other abnormalities such as acute pancreatitis, oral cancer and severe myopia [7,9,10]. Whether SNTB1 has a pathological role in CRC is unknown.…”
Section: Read Full Licensementioning
confidence: 99%
“…Furthermore, genetic research has been widely conducted for MMP2 using human population. The MMP‐2 C1306T (rs243865) was found to be associated with a wide range of diseases, including the risk of cervical cancer, 29 colorectal cancer, 16 and coronary artery disease, 30 susceptibility to salivary gland cancer 31 and oesophageal squamous cell carcinoma, 14 chronic obstructive pulmonary disease severity, 17 intracranial aneurysm, 32 and oral cancer 33 . In the female group, the association between MMP‐2 C‐735T and risk of multiple sclerosis was statistically significant 15 .…”
Section: Discussionmentioning
confidence: 99%
“…As previous studies, CNTN4 SNV has been found to be associated with several diseases. For example, rs9849237 (CNTN4) CC genotype is related to an increased risk of oral cancer in an Indian cohort [30]. CNTN4 is overexpressed in pheochromocytoma and paraganglioma Fig.…”
Section: Discussionmentioning
confidence: 99%