Single Organ Vasculitis

Hernández‐Rodríguez, José; Hoffman, Gary S.

doi:10.1002/9781118355244.ch30

Cited by 5 publications

(7 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…He was discharged without further complications. Polyarteritis nodosa of a muscle is quite rare and has been reported to be restricted to the lower legs (1,2). To our knowledge, this is the first reported case of polyarteritis nodosa confined to the iliopsoas muscle.…”

Section: Watson L Midgleymentioning

confidence: 73%

Polyarteritis Nodosa of the Iliopsoas Muscle

Taniguchi¹,

Ogata²,

Yoshimatsu³

et al. 2015

Arthritis & Rheumatology

View full text Add to dashboard Cite

Section: Watson L Midgleymentioning

confidence: 73%

Polyarteritis Nodosa of the Iliopsoas Muscle

Taniguchi¹,

Ogata²,

Yoshimatsu³

et al. 2015

Arthritis & Rheumatology

View full text Add to dashboard Cite

“…The diagnosis of SOV, including LVGT, requires no additional source of vascular inflammation at both the time of diagnosis and over a 6-month follow-up period. 16 Localized vasculitis of the GI tract was considered in patients with recent history or presence of acquired GI manifestations (including abdominal pain, nausea or vomiting, diarrhea, weight loss, melena) and a histopathological evidence of vasculitis in a GI specimen; or high-probability angiographic findings (smooth segmental narrowing, dilatation, occlusion or aneurysms affecting one or more GI arteries) with significant wall thickening (⩾ 3 mm) and the absence of vessel changes consistent with atherosclerosis, FMD or SAM). 17 Inflammatory markers can be normal or elevated.…”

Section: Methodsmentioning

confidence: 99%

Segmental arterial mediolysis (SAM): Systematic review and analysis of 143 cases

et al. 2019

View full text Add to dashboard Cite

Segmental arterial mediolysis (SAM) is a rare but serious nonatherosclerotic, noninflammatory vasculopathy of unknown etiology that often results in dissection, aneurysm, occlusion, or stenosis of, primarily, the abdominal arteries. Current literature lacks consensus on diagnostic criteria and management options for SAM. This review summarizes 143 cases and aims to advance appropriate recognition and management of SAM. Literature review of all relevant SAM case studies from 2005 to 2018 yielded 126 individual SAM cases from 66 reports. We identified 17 additional SAM cases from our center, bringing our analysis to 143 patients. Patients with SAM were most commonly men (68%) in their 60s. Hypertension (43%), tobacco use (12%), and hyperlipidemia (12%) were common comorbidities. Abdominal pain (80%) and intraabdominal bleeding (50%) were the most common presenting symptoms. Computed tomography was the most frequently used imaging method (78%), and histology was available in 44% of cases. The most commonly affected vessels were the superior mesenteric (53%), hepatic (45%), celiac (36%), renal (26%), and splenic (25%) arteries with aneurysm (76%), dissection (61%), and arterial rupture (46%). Treatments included coil embolization (28%), abdominal organ surgery (24%), open arterial repair (21%), and medical management (20%). Case-specific treatment modalities yielded symptom relief in the vast majority (91%) of patients, with a mortality rate of 7%.

show abstract

“…The other commonly reported sites of single-organ vasculitis are the breasts, genitourinary tract and the GI tract. 48 The largest series of localized GI vasculitis consists of 18 patients. 49 In addition, there have been several case reports in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…49 While cure can be achieved in the former with surgical resection alone, isolated vasculitis of the intestines has a more aggressive course with variable prognoses, more often than not requiring immunosuppression following surgical resection, as exemplified by our patient. 48,[54][55][56] As was the case in this patient, a definite diagnosis of localized GI vasculitis can be made only after excluding a systemic vasculitis or connective tissue disorder through serological tests and a diligent search for the involvement of other organ systems, and also after prolonged follow-up surveillance, if the disease remains confined to the GI tract. 57,58 This case also highlights the challenges faced by the treating physicians when the family refuses to go for the best form of therapy due to fears of side effects over and above the looming threat of death due to the disease.…”

Section: Discussionmentioning

confidence: 99%