Nanoscale single-electron pumps can be used to generate accurate currents, and can potentially serve to realize a new standard of electrical current based on elementary charge. Here, we use a silicon-based quantum dot with tunable tunnel barriers as an accurate source of quantized current. The charge transfer accuracy of our pump can be dramatically enhanced by controlling the electrostatic confinement of the dot using purposely engineered gate electrodes. Improvements in the operational robustness, as well as suppression of non-adiabatic transitions that reduce pumping accuracy, are achieved via small adjustments of the gate voltages. We can produce an output current in excess of 80 pA with experimentally determined relative uncertainty below 50 parts per million.As early as one and a half centuries ago, J. C. Maxwell envisaged the need for a system of standards based on phenomena at the atomic scale and directly related to invariant constants of nature. 1 However, Maxwell could not anticipate that, in order to harness the behaviour of the world at the nanometer scale, a completely new physical interpretation was needed, namely, quantum mechanics. At first, the laws of quantum mechanics seemed to reveal fundamental limits to the accuracy of physical measurements. Concepts like the Heisenberg uncertainty principle, which imposes intrinsic fluctuations on the values of non-commuting observables, and the wavefunction collapse, responsible for the randomization of a system configuration after performing a measurement, appeared to be at odds with the requirement of deterministic consistency that is paramount for metrological purposes. Nevertheless, quantum-based systems are today acknowledged as the most stable and reliable metrological tools, as they can be strongly intertwined with fundamental constants. Exquisitely quantum-mechanical phenomena such as the ac Josephson effect 2 and the quantum Hall effect 3 have paved the way towards new and more reliable reference standards for the units of voltage and resistance, respectively.Major efforts are currently ongoing to re-define the unit of electrical current, the ampere (A), in terms of the elementary charge, e, by means of quantum technologies 4,5 . A practical implementation of this standard may be the electron pump, a device in which a quantum phenomenon, namely tunnelling, and classical Coulomb repulsion, are combined to control the transfer of an integer number of elementary charges. This device ideally generates a quantized output current, I P = nef , where n is an integer and f is the frequency of an external periodic drive. Several enabling technologies have already been developed including metal/oxide tunnel barrier devices 6,7 , normal-metal/superconductor turnstiles 8,9 , graphene double quantum dots 10 , donor-based pumps 11-13 , silicon-based quantum dot pumps 14-18 and GaAs-based quantum dot pumps [19][20][21][22][23][24][25][26][27] . To date, the latter scheme provides the lowest uncertainty of 1.2 parts per million (ppm) yielding current in excess o...