“…Recently, innovations in the technology such as multi-channel single-port, articulating instruments, and flexible endoscopes have allowed laparoscopic surgeons to perform increasingly complex gynecological and gynecologic-oncologic operations. [2][3][4][5][6][7] A recent systematic review by Mencaglia et al identified 65 studies (17 case reports, 32 cases studies, 13 retrospective comparative studies and three randomized clinical trials) and reported that LESS is safe and feasible for most benign gynecologic surgeries. 8 A randomized clinical trial that evaluated LESS compared to conventional laparoscopic-assisted vaginal hysterectomy reported significant decreases in post-operative pain and analgesic use in the LESS-assisted vaginal hysterectomy group.…”