“…However, these changes can be problems if the surgery lasts longer than expected or when the patient is at risk of abnormal ventilation, even from subtle changes. Most articles on SITS bleb resection focused on the feasibility of that surgery without objective evidence (3,4,13,16). They reported the feasibility of SITS with CO 2 insufflation in terms of operation time, anesthesia time, postoperative complications, hospital stay, subjective operation field evaluation and physiologic changes (3,4,13).…”