“…However, high-dose systemic opioids may increase the incidence of undesirable adverse effects, such as respiratory depression, nausea, and vomiting. In recent years, regional anesthesia techniques, including intercostal nerve blocks (ICNBs), have been implemented in children undergoing the Nuss procedure 8,9. The advantages of ICNBs include technical simplicity, good analgesia, an opioid-sparing effect, improved pulmonary mechanics, reduced central nervous system (CNS) depression, and avoidance of urinary retention 10.…”