Abstract:BackgroundSingle-stage repair of incisional hernias in contaminated fields has a high rate of surgical site infection (30-42%) when biologic grafts are used for repair. In an attempt to decrease this risk, a novel graft incorporating gentamicin into a biologic extracellular matrix derived from porcine small intestine submucosa was developed. MethodsThis prospective, multicenter, single-arm study was designed to determine the incidence of surgical site infection following implantation of the device into surgica… Show more
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