Single Subject Designs in Biomedicine

Janosky, Janine E.

doi:10.1007/978-90-481-2444-2

Cited by 35 publications

(40 citation statements)

References 169 publications

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“…52 Moreover, this type of design has utility in measuring the magnitude of the outcome changes. 53,54 In order to eliminate some of the threats to the internal validity of the AB design, we provided several inter-subjects replications of the AB sequence.…”

Section: Experimental Designmentioning

confidence: 99%

Can the Social Robot Probo Help Children With Autism to Identify Situation-Based Emotions? A Series of Single Case Experiments

Pop

Simut

Pintea

et al. 2013

Int. J. Human. Robot.

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Children with autism spectrum disorders have di±culties in identifying situation-based emotions, which is a fundamental ability for mind reading. Social robots received increased attention as assisting tools for improving the social and emotional skills of children with autism. This study investigates whether the social robot Probo can help children with autism spectrum disorders to enhance their performance in identifying situation-based emotions. Three participants (age between 5 and 6) diagnozed with autism spectrum disorders were included in a single case AB experimental design, with intersubjects replications. The results show that children's performance improved with moderate to large e®ect sizes in identifying both sadness and happiness. Based on these results, we intend to perform more extensive investigations regarding the e®ectiveness of robot assisted therapy in improving social-emotional abilities for children with autism spectrum disorders.

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Section: Experimental Designmentioning

confidence: 99%

Can the Social Robot Probo Help Children With Autism to Identify Situation-Based Emotions? A Series of Single Case Experiments

Pop

Simut

Pintea

et al. 2013

Int. J. Human. Robot.

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show abstract

“…The Glasgow Hearing Aid Benefit Profile (GHABP) [20] and the Abbreviated Profile of Hearing Aid Benefit (APHAB) [21] were completed after each experimental phase to collect participants' perspectives on the benefits of each technology. Speech recognition data were first analyzed on an individual basis, using a visual analysis method [22,23]. Results to each test session were graphed, by outcome, and separately for each participant.…”

Section: Methodsmentioning

confidence: 99%

Effectiveness of Frequency-Lowering Hearing Aids and Electric Acoustic Stimulation Cochlear Implant for Treating People with a Severe-To-Profound High-Frequency Hearing Loss

Hotton

Bergeron

2017

JOENTR

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“…We used an A-B-A single-subject experimental design in order to allow for statistical analysis of effect size while controlling for threats to internal and external validity [20][21][22]. MIP and MEP were selected as co-primary dependent variables due to their noninvasive nature and high correlation with invasive measures of respiratory strength [23].…”

Section: Experimental Designmentioning

confidence: 99%

Effects of respiratory muscle training (RMT) in children with infantile-onset Pompe disease and respiratory muscle weakness

Jones

Crisp

Moss

et al. 2014

Journal of Pediatric Rehabilitation Medicine

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PURPOSE: Respiratory muscle weakness is a primary therapeutic challenge for patients with infantile Pompe disease. We previously described the clinical implementation of a respiratory muscle training (RMT) regimen in two adults with late-onset Pompe disease; both demonstrated marked increases in inspiratory and expiratory muscle strength in response to RMT. However, the use of RMT in pediatric survivors of infantile Pompe disease has not been previously reported. METHOD: We report the effects of an intensive RMT program on maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) using A-B-A (baseline-treatment-posttest) single subject experimental design in two pediatric survivors of infantile Pompe disease. Both subjects had persistent respiratory muscle weakness despite long-term treatment with alglucosidase alfa. RESULTS: Subject 1 demonstrated negligible to modest increases in MIP/MEP (6% increase in MIP, d = 0.25; 19% increase in MEP, d = 0.87), while Subject 2 demonstrated very large increases in MIP/MEP (45% increase in MIP, d = 2.38; 81% increase in MEP, d = 4.31). Following three-month RMT withdrawal, both subjects maintained these strength increases and demonstrated maximal MIP and MEP values at follow-up. CONCLUSION: Intensive RMT may be a beneficial treatment for respiratory muscle weakness in pediatric survivors of infantile Pompe disease.

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Single Subject Designs in Biomedicine

Cited by 35 publications

References 169 publications

Can the Social Robot Probo Help Children With Autism to Identify Situation-Based Emotions? A Series of Single Case Experiments

Can the Social Robot Probo Help Children With Autism to Identify Situation-Based Emotions? A Series of Single Case Experiments

Effectiveness of Frequency-Lowering Hearing Aids and Electric Acoustic Stimulation Cochlear Implant for Treating People with a Severe-To-Profound High-Frequency Hearing Loss

Effects of respiratory muscle training (RMT) in children with infantile-onset Pompe disease and respiratory muscle weakness

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