Single Wall Carbon Nanotubes Functionalized with Composition of $\gamma$-Aluminum Oxide and Polydimethylsiloxane Properties

Лыков, А. П.; Vi, Konenkov; Rachkovskaya, L. N.; Повещенко, О. В.; Суровцева, М. А.; Kim, Irina; Bondarenko, N. A.; Yankaite, E. V.; Rachkovsky, Edmond; Volodin, Alexander M.

doi:10.1109/sibircon48586.2019.8958186

Cited by 2 publications

(4 citation statements)

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“…The water absorption test was performed to determine which of the Ag-Si/Al 2 O 3 sorbents (1)(2)(3)(4) show the best absorption capability. Been a sorbent a substance which has the property of collecting molecules of another substance by sorption, and are commonly used as materials for blood purification and hemodialysis [53][54][55][56][57][58][59].…”

Section: Water Uptake Testmentioning

confidence: 99%

Electrospun Fibers and Sorbents as a Possible Basis for Effective Composite Wound Dressings

et al. 2020

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Skin burns and ulcers are considered hard-to-heal wounds due to their high infection risk. For this reason, designing new options for wound dressings is a growing need. The objective of this work is to investigate the properties of poly (ε-caprolactone)/poly (vinyl-pyrrolidone) (PCL/PVP) microfibers produced via electrospinning along with sorbents loaded with Argovit™ silver nanoparticles (Ag-Si/Al2O3) as constituent components for composite wound dressings. The physicochemical properties of the fibers and sorbents were characterized using scanning electron microscopy (SEM), differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR) and inductively coupled plasma optical emission spectroscopy (ICP-OES). The mechanical properties of the fibers were also evaluated. The results of this work showed that the tested fibrous scaffolds have melting temperatures suitable for wound dressings design (58–60 °C). In addition, they demonstrated to be stable even after seven days in physiological solution, showing no macroscopic damage due to PVP release at the microscopic scale. Pelletized sorbents with the higher particle size demonstrated to have the best water uptake capabilities. Both, fibers and sorbents showed antimicrobial activity against Gram-negative bacteria Pseudomona aeruginosa and Escherichia coli, Gram-positive Staphylococcus aureus and the fungus Candida albicans. The best physicochemical properties were obtained with a scaffold produced with a PCL/PVP ratio of 85:15, this polymeric scaffold demonstrated the most antimicrobial activity without affecting the cell viability of human fibroblast. Pelletized Ag/Si-Al2O3-3 sorbent possessed the best water uptake capability and the higher antimicrobial activity, over time between all the sorbents tested. The combination of PCL/PVP 85:15 microfibers with the chosen Ag/Si-Al2O3-3 sorbent will be used in the following work for creation of wound dressings possessing exudate retention, biocompatibility and antimicrobial activity.

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Section: Water Uptake Testmentioning

confidence: 99%

Electrospun Fibers and Sorbents as a Possible Basis for Effective Composite Wound Dressings

et al. 2020

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“…Splenocyte (Sp) and thymocytes (Th) were transplanted in RPMI-1640 (Biolot, Russia) medium with the addition of 80 µg/mL of gentamicin, 2 mmol L-glutamine, 5 mmol HEPES-buffer and 10% FCS at a concentration 10 6 cells/mL. Splenocytes and thymocytes viability and proliferation activity in presence of Fx@Al/PDMS in dosage 0 µg and 0.057 µg was detected by 3-(4,5-dimethylyhiazol-2-yl)-2,5-diphenyltetrazolium bromide DOI 10.18502/kls.v7i1.10109 8th Scientific and Practical Conference (Merck, USA) assay after 24 h (short-term exposure) and 120 h (long-term exposure) [5]. Nitric oxide (NO) production by splenocytes or thymocytes was measured in supernatants using Griess reagent for nitrite determination (Merck, USA) [5].…”

Section: Methodsmentioning

confidence: 99%

“…Splenocytes and thymocytes viability and proliferation activity in presence of Fx@Al/PDMS in dosage 0 µg and 0.057 µg was detected by 3-(4,5-dimethylyhiazol-2-yl)-2,5-diphenyltetrazolium bromide DOI 10.18502/kls.v7i1.10109 8th Scientific and Practical Conference (Merck, USA) assay after 24 h (short-term exposure) and 120 h (long-term exposure) [5]. Nitric oxide (NO) production by splenocytes or thymocytes was measured in supernatants using Griess reagent for nitrite determination (Merck, USA) [5]. Myeloperoxidase activity was detected by mixture of 1 part of 0.6% solution of benzidine (Merck, USA) based on a 96% solution of C 2 H 5 OH, and 2.5 parts of a mixture of 0.25 ml of 33.4% H 2 O 2 (Merck, USA) of 2.25 ml of 70% solution of C 2 H 5 OH in splenocytes or thymocytes [5].…”

Section: Methodsmentioning

confidence: 99%

“…Nitric oxide (NO) production by splenocytes or thymocytes was measured in supernatants using Griess reagent for nitrite determination (Merck, USA) [5]. Myeloperoxidase activity was detected by mixture of 1 part of 0.6% solution of benzidine (Merck, USA) based on a 96% solution of C 2 H 5 OH, and 2.5 parts of a mixture of 0.25 ml of 33.4% H 2 O 2 (Merck, USA) of 2.25 ml of 70% solution of C 2 H 5 OH in splenocytes or thymocytes [5].…”

Section: Methodsmentioning

confidence: 99%

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The Influence of Fucoxanthin Immobilized on Porous Aluminum-Silicon Carrier Surface on the Functional Activities of Immunocytes in Mice

Лыков

Rachkovskaya

Gevorgiz³

et al. 2022

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Fucoxanthin is a natural carotenoid obtained from seaweed which exhibits antioxidant properties. This research aimed to assess whether fucoxanthin, immobilized on aluminum-silicon carrier particles, has a toxic effect on immune cells. The viability, proliferation, nitric oxide production and myeloperoxidase activity of thymocytes and splenocytes of mice in vitro were studied. It was shown that fucoxanthin, immobilized on aluminum-silicon carrier particles, increased the survival rate and proliferation of mature immunocytes (splenocytes) after 24 hours exposure and increased the survival rate of naïve immunocytes (thymocytes) when exposed for 120 hours. In terms of myeloperoxidase, the activity of the immune cells was not affected by fucoxanthin immobilized on the carrier particles. The obtained results indicated that fucoxanthin, immobilized on particles of an aluminum-silicon carrier, did not have a toxic effect on mouse immunocytes. Keywords: Cylindrotheca closterium, fucoxanthin, γ-aluminum oxide, polydimethylsiloxane, thymocytes, splenocytes, viability, proliferation, nitric oxide, myeloperoxidase activity

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Single Wall Carbon Nanotubes Functionalized with Composition of $\gamma$-Aluminum Oxide and Polydimethylsiloxane Properties

Cited by 2 publications

References 5 publications

Electrospun Fibers and Sorbents as a Possible Basis for Effective Composite Wound Dressings

Electrospun Fibers and Sorbents as a Possible Basis for Effective Composite Wound Dressings

The Influence of Fucoxanthin Immobilized on Porous Aluminum-Silicon Carrier Surface on the Functional Activities of Immunocytes in Mice

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