The existence of both a minimum mass and a minimum density in nature, in the presence of a positive cosmological constant, is one of the most intriguing results in classical general relativity. These results follow rigorously from the Buchdahl inequalities in four-dimensional de Sitter space. In this work, we obtain the generalized Buchdahl inequalities in arbitrary space-time dimensions with = 0 and consider both the de Sitter and the anti-de Sitter cases. The dependence on D, the number of space-time dimensions, of the minimum and maximum masses for stable spherical objects is explicitly obtained. The analysis is then extended to the case of dark energy satisfying an arbitrary linear barotropic equation of state. The Jeans instability of barotropic dark energy is also investigated, for arbitrary D, in the framework of a simple Newtonian model with and without viscous dissipation, and we determine the dispersion relation describing the dark energy-matter condensation process, along with estimates of the corresponding Jeans mass (and radius). Finally, the quantum mechanical implications of the mass limits are investigated, and we show that the existence of a minimum mass scale naturally leads to a model in which dark energy is composed of a 'sea' of quantum particles, each with an effective mass proportional to 1/4 .