Sinonasal Myxoma With Intraorbital Expansion: A Rare Case

Kondamuri, Neil; Bharathi, R. Krishna; Woo, Albert S.; Groblewski, Jan C.

doi:10.1177/2473974x211045300

Cited by 5 publications

(1 citation statement)

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“…In the field of the face and head, myxoma has been rarely detected in the orbit, [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] cornea, 23 and conjunctiva [24][25][26][27] of the ocular surface, eyelid, [28][29][30] nasal cavity, and paranasal sinuses. [31][32][33][34][35][36][37][38][39][40] We experienced a patient with orbital myxoma who showed connection with the ethmoid sinus lesion in the follow-up period of 20 years before and after surgical resection of the orbital lesions. We also reviewed 20 patients with orbital myxomas in the literature to know their clinical features.…”

Section: Introductionmentioning

confidence: 99%

Resection of Orbital Myxoma With Magnetic Resonance Imaging Evidence of Ethmoid Sinus Origin: Case Report and Review of 20 Patients in the Literature

Matsuo,

Tanaka

2023

Journal of Investigative Medicine High Impact Case Reports

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A 41-year-old woman showed a palpable mass at the superonasal orbital edge on the right side. Magnetic resonance imaging demonstrated a lobulated fluid-containing tubular mass which extended anteriorly to posteriorly along the medial orbital wall, nasal to the eyeball. She was followed once a year for 8 years until the age of 49 years when she decided to undergo surgical resection because of the enlarged mass. The lobulated large mass was resected and the pathology showed sparsely distributed spindle cells, positive for CD34, in alcian blue-positive mucous substances, indicative of myxoma. Postoperative magnetic resonance imaging showed residual lobulated tubular mass along the optic nerve on the medial side and superior to the eyeball. The residual orbital mass showed stable structure with more evident connection with the ethmoid sinus lesion, suggestive of the ethmoid origin, in 12 years until the age of 61 years. In the review of 20 patients with orbital myxomas in the literature, in addition to this case, roughly classified locations in the orbit were retrobulbar in 8 patients, on the lateral side of the orbit in 4, on the superior side in 6, on the medial side in 1 (this patient), and in the orbit with no specific description in 2. In pathological examinations, immunohistochemistry was not done in 8 patients, done but all negative in 2, and positive in 11 patients: nerve sheath myxoma was diagnosed in 3 patients based on positive S100 staining. Orbital myxoma is rare but considered in differential diagnosis of orbital masses.

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Section: Introductionmentioning

confidence: 99%

Resection of Orbital Myxoma With Magnetic Resonance Imaging Evidence of Ethmoid Sinus Origin: Case Report and Review of 20 Patients in the Literature

Matsuo,

Tanaka

2023

Journal of Investigative Medicine High Impact Case Reports

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Sinonasal Myxoma: A Distinct Entity or a Myxoid Variant of Desmoid Fibromatosis?

Torres

Mata²,

Briski

et al. 2023

Modern Pathology

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Pediatric Odontogenic Myxoma: A Case Report and a Systematic Review of the Literature

Mckenzie

Charles

Simpson

et al. 2022

FACE

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Purpose: Odontogenic myxoma (OM) is a benign, locally invasive odontogenic tumor, which has been historically treated with en bloc resection to prevent recurrence. In pediatric patients en bloc resection is associated with significant morbidity in relation to growth, function, cosmesis, and the associated risks of radical surgery. Methods: This research aims to present an up-to-date series of OM in pediatric patients (0-3 years), to evaluate treatment approaches and recurrence in this population, and provide treatment recommendations through the presentation of a case report in a 15-month-old child and a systematic review of the literature. MEDLINE (PubMed), Scopus, Science Direct, Google Scholar, and Cochrane Database of Systematic Reviews were searched in August 2021 in accordance with the PRISMA guidelines. Results: In total 53 patients were identified with OM. Pediatric OM occurs more frequently in males, in the maxilla, presenting most commonly with swelling, with a mean duration of onset of 9 weeks (6-12 weeks, 95% CI). The rates of recurrence in OM were low (5/53, 9%) with no recurrences in patients treated with enucleation with peripheral ostectomy or adjunctive procedures including cryotherapy or Carnoy’s solution, indicating that they can be used successful as first line treatment, reducing patient morbidity. Conclusion: Pediatric odontogenic myxoma occurs most frequently in males, within the maxilla and can be treated successfully with conservative surgical management with enucleation, peripheral ostectomy with the application of Carnoy’s solution or Cryotherapy, reducing patient morbidity. Patients should be followed up clinically and radiographically to monitor for recurrence, which primarily occurs within the first 12 months of treatment.

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Sinonasal Myxoma With Intraorbital Expansion: A Rare Case

Cited by 5 publications

References 1 publication

Resection of Orbital Myxoma With Magnetic Resonance Imaging Evidence of Ethmoid Sinus Origin: Case Report and Review of 20 Patients in the Literature

Resection of Orbital Myxoma With Magnetic Resonance Imaging Evidence of Ethmoid Sinus Origin: Case Report and Review of 20 Patients in the Literature

Sinonasal Myxoma: A Distinct Entity or a Myxoid Variant of Desmoid Fibromatosis?

Pediatric Odontogenic Myxoma: A Case Report and a Systematic Review of the Literature

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