Sinonasal seromucinous hamartoma

Abstract

Sinonasal SH is a rare diagnosis characterized by a polypoid lesion with a haphazard proliferation of seromucinous glands. The rhinologists should consider it in the differential diagnosis of a polypoid lesion in the nasal cavity.

Middle Turbinate Seromucinous Hamartoma in a Patient With Primary Atrophic Rhinitis

“…1 This lesion typically arises on the posterior nasal septum and in the nasopharynx, although SH has also been observed on the lateral nasal wall. 1,2 Only 39 cases of SH have been previously described in the literature. [1][2][3][4][5] The male to female ratio is 3:2.…”

“…1,2 Only 39 cases of SH have been previously described in the literature. [1][2][3][4][5] The male to female ratio is 3:2. 1 The most common symptoms are nasal obstruction, mucopurulent secretion, and epistaxis.…”

“…[1][2][3][4][5] The male to female ratio is 3:2. 1 The most common symptoms are nasal obstruction, mucopurulent secretion, and epistaxis. It is unclear whether these lesions are true benign neoplasms or developmental tumor-like lesions.…”

“…It is unclear whether these lesions are true benign neoplasms or developmental tumor-like lesions. [1][2][3][4][5] According to the 4th edition of the World Health Organization Classification of Head and Neck Tumors, SH and respiratory epithelial adenomatoid hamartoma (REAH) are classified as ''respiratory epithelial lesions.'' 6 The differential diagnosis for SH includes inflammatory nasal polyps, REAH, and low-grade sinonasal adenocarcinoma (LGSNA).…”

“…Seromucinous hamartoma is characterized by numerous seromucinous glands, which are not present in inflammatory polyps. [1][2][3][4][5] The stroma of inflammatory polyps is more edematous and the surface is smooth. 1 REAH is the most common hamartoma in the sinonasal tract, characterized by proliferation of pseudostratified respiratory epithelium-lined pseudoglands.…”