Sinonasal Wegener granulomatosis: A single‐institution experience with 120 cases

Cannady, Steven B.; Batra, Pete S.; Koening, Curry L.; Lorenz, Robert R.; Citardi, Martin J.; Langford, Carol A.; Hoffman, Gary S.

doi:10.1002/lary.20161

Cited by 118 publications

(123 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some series suggest that surgery for CRS, mucocele formation, and nasolacrimal stenosis may be beneficial to control sequelae of GPA for appropriately selected patients. 1441 Systemic manifestations of both sarcoidosis and ChurgStrauss syndrome are managed with chemotherapeutic agents, oral corticosteroids ± immune modulators, but like GPA, the literature supports use of medical management while reserving surgical intervention for persistent rhinologic symptoms in select patients. [1442][1443][1444][1445][1446] Given the epithelial abnormalities present in CGD patients, patients should be counseled regarding suboptimal and/or delayed healing that can follow intranasal procedures.…”

Section: Special Considerations In Rhinosinusitis Xiia Rs Specmentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

Self Cite

557

888

View full text Add to dashboard Cite

Background:The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods:Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results:The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AE-CRS), and pediatric RS. Conclusion:As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too o en the foundation upon which these recommendations are based is comprised of lowerlevel evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed. C 2016 ARS-AAOA, LLC. Key Words:rhinosinusitis; chronic rhinosinusitis; acute rhinosinusitis; recurrent acute rhinosinusitis; evidence-based medicine; systematic review; endoscopic sinus surgery List of Abbreviations Used

show abstract

Section: Special Considerations In Rhinosinusitis Xiia Rs Specmentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

Self Cite

557

888

View full text Add to dashboard Cite

show abstract

“…Head and neck manifestations are common and are exhibited in 72% to 99% ofpatients at some point in their disease course. Sinonasal involvement is the most frequent ofthe head and neck manifestations, occurring in approximately 85% of patients (2). It may cause chronic rhinosinusitis, septal perforations, saddle-nose deformity and paranasal sinus mucocele formation from chronic outflow tract obstruction.…”

Section: Discussionmentioning

confidence: 99%

Meningeal Involvement in Wegener Granulomatosis: Case Report and Review of the Literature

Soriano

Vullo

Casale

et al. 2012

Int J Immunopathol Pharmacol

View full text Add to dashboard Cite

Wegener Granulomatosis (WG) is a multisystem autoimmune disorder characterized by necrotizing granulomatous vasculitis that most commonly involves the upper respiratory tract, lungs, and kidneys. The involvement of the central nervous system (CNS) is infrequent and can cause stroke, cranial nerve abnormalities, cerebrovascular events, seizures, and meningeal involvement. Meningeal involvement is rare and may occur due to local vasculitis, directly spread from adjacent disease in the skull base, paranasal or orbital region. We describe the case ofa 20-year-old Caucasian man who was diagnosed with sinonasal WG with frontal focal meningeal involvement. A literature review on diagnosis and treatment of meningeal involvement in course of WG was carried out. The importance of an early diagnosis and treatment of localized WG has been emphasized, in order to avoid the progression to a severe form of disease, especially in younger patients and in paucisymptomatic cases. Case reportA twenty-year-old Caucasian man with history of parietaria allergy presented with nasal congestion, occasional epistaxis and purulent rhinorrhea that had started 1 year previously. He had been seen at another hospital and had received a diagnosis of allergic rhinosinusitis. Large doses of intranasal steroids and multiple courses ofantibiotic therapy did not result in an improvement. An X-ray of the paranasal sinuses carried out six months previously was negative. His familial history was unremarkable; his parents were both living and well; the patient was the only child, he was a medical student at University in his own city, he was single and lived with his parents. He had no allergies to medications, and he denied use of alcohol, illicit drugs and smoking.On admission to our Department, headache, neck stiffness, dyspnoea, cough, fever, night sweats, fatigue, myalgia or arthralgia were absent. On examination, the patient was alert, oriented, and cooperative. There was nasal congestion and copious discharge. The lungs were clear on the auscultation, the cardiac and abdominal examinations were normal. Neurologic examination was negative for focal motor or sensory deficits as well as examination of cranial nerves II through XII. A complete blood count revealed a white-cell count of 8,430 per cubic millimeter, with 46% polymorphonuclear cells. The hematocrit was 41%, and the platelet count 296,000 per cubic millimeter. The blood urea nitrogen level was 27 mg per deciliter, and the creatinine level 0.70 mg per deciliter. Erythrocyte sedimentationrate (ESR)

show abstract

“…Дефект перегородки носа может быть проявле нием системных заболеваний соединительной тка ни [27], таких как гранулематоз Вегенера [28], ми кроскопический полиангиит и синдром Чарга-Стросса [29]. Роль системных заболеваний в воз никновении перфорации связана с нарушением кровоснабжения слизистой оболочки и хряща пере городки носа [30].…”

Section: перфорация перегородки носаunclassified

Iatrogenic abnormalities of the nasal cavity: A review of literature

Bazarkina¹

2016

Ross. rinol.

View full text Add to dashboard Cite

К.П. БАЗАРКИНАФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента Российской Федерации, Москва, Россия В статье представлен обзор клинических исследований, посвященных изучению распространенности, диагностике и лечению таких ятрогенных состояний, как синдром пустого носа, перфорация перегородки и синехии полости носа. Значительное внимание уделено вопросам консервативного и хирургического лечения данных патологий. This paper reviews clinical studies dealing with the prevalence, diagnosis, and treatment of iatrogenic conditions, such as empty nose syndrome, nasal septal perforation, and nasal synechiae. Considerable attention is paid to the medical and surgical treatment of this condition.

show abstract

Sinonasal Wegener granulomatosis: A single‐institution experience with 120 cases

Cited by 118 publications

References 15 publications

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Meningeal Involvement in Wegener Granulomatosis: Case Report and Review of the Literature

Iatrogenic abnormalities of the nasal cavity: A review of literature

Contact Info

Product

Resources

About