Sinus Arrhythmia in Acute Myocardial Infarction

Mm, Wolf; Ga, Varigos; Hunt, David; Jg, Sloman

doi:10.5694/j.1326-5377.1978.tb131339.x

Cited by 382 publications

(155 citation statements)

References 2 publications

Supporting

Mentioning

126

Contrasting

Unclassified

Order By: Relevance

“…The interest of cardiologists in the heart rate variability was initiated by Wolf [4], who studied 176 patients with acute myocardial infarction and stated that a decrease in HRV is associated with poor prognosis. According to the published study results, patients with heart failure, ischaemic heart disease, myocardial infarction, hypertension, diabetes, psychiatric disorders, neonatal diseases and low parameters of parasympathetic nervous system activity present a risk of cardiac death [4–7].…”

Section: Discussionmentioning

confidence: 99%

Heart rate variability in children with aortic valve stenosis – a pilot study

Werner

Piórecka-Makuła²,

Bobkowski³

2013

aoms

View full text Add to dashboard Cite

IntroductionThe aim of our prospective study was to evaluate heart rate variability (HRV) in children with aortic valve stenosis (AS) and its relationship with left ventricular mass and peak transaortic valve pressure gradient (PG).Material and methodsSixty children with AS divided into 3 groups according to their PG and 60 healthy controls were studied. Holter ECG monitoring with time domain HRV analysis was performed. Left ventricular mass was calculated by echocardiography.ResultsMean values of all HRV parameters were statistically significantly lower (p < 0.001) in children with AS than in controls (respectively: SDNN 127.8 ±28.2 ms; 162.6 ±38.0 ms, SDNN day 99.7 ±26.6 ms; 134.1 ±36.1 ms, SDNN night 99.9 ±32.8 ms; 123.4 ±45.7 ms, SDANN 112.2 ±27.7 ms; 142.4 ±34.6, SDNNi 62.2 ±16.2 ms; 75.9 ±21.6, RMSSD 39.6 ±12.1 ms; 50.3 ±16.7 ms, rMSSD day 33.6 ±10.9 ms; 43.1 ±14.7 ms, rMSSD night 49.8 ±18.1 ms; 64.4 ±24.9 ms, pNN50 16.4 ±9.5%; 23.5 ±11.7%, pNN50 day 12.0 ±8.5%; 18.4 ±10.7%, pNN50 night; 26.5 ±14.8%; 36.4 ±17.4%. No significant differences between the mean values of HRV parameters in children with different PG and with and without myocardial hypertrophy were found. In children with AS and ventricular arrhythmia SDNN day was significantly lower (p < 0.05) compared to patients without arrhythmia (94.9 ±22.1 ms vs. 109.3 ±22.5 ms).ConclusionsIn children with AS the balance of the autonomic nervous systemic disturbed which manifests in an increase in sympathetic and decrease in parasympathetic activity. Transaortic valve pressure gradient and myocardial hypertrophy do not influence the HRV. The SDNN reduction during the day period may indicate the risk of ventricular arrhythmia in children with AS.

show abstract

Section: Discussionmentioning

confidence: 99%

Heart rate variability in children with aortic valve stenosis – a pilot study

Werner

Piórecka-Makuła²,

Bobkowski³

2013

aoms

View full text Add to dashboard Cite

show abstract

“…In 1965, Schneider and Costiloe presented evidence that MI patients had less sinus arrhythmia – a component of HRV associated with respiration – than did healthy controls 34. In 1978, Wolf et al reported that among patients admitted to a coronary care unit (CCU), those showing evidence of sinus arrhythmia upon admission tended to have less mortality and better prognosis 35. A seminal 1987 study by Kleiger et al demonstrated that low HRV, measured with Holter recorders (ambulatory electrocardiography device) 2 weeks post-MI, was independently associated with all-cause mortality during 31 months of follow-up 3.…”

Section: The Reviewmentioning

confidence: 99%

Heart rate variability measurement and clinical depression in acute coronary syndrome patients: narrative review of recent literature

Harris

Sommargren²,

Stein³

et al. 2014

NDT

View full text Add to dashboard Cite

AimWe aimed to explore links between heart rate variability (HRV) and clinical depression in patients with acute coronary syndrome (ACS), through a review of recent clinical research literature.BackgroundPatients with ACS are at risk for both cardiac autonomic dysfunction and clinical depression. Both conditions can negatively impact the ability to recover from an acute physiological insult, such as unstable angina or myocardial infarction, increasing the risk for adverse cardiovascular outcomes. HRV is recognized as a reflection of autonomic function.MethodsA narrative review was undertaken to evaluate state-of-the-art clinical research, using the PubMed database, January 2013. The search terms “heart rate variability” and “depression” were used in conjunction with “acute coronary syndrome”, “unstable angina”, or “myocardial infarction” to find clinical studies published within the past 10 years related to HRV and clinical depression, in patients with an ACS episode. Studies were included if HRV measurement and depression screening were undertaken during an ACS hospitalization or within 2 months of hospital discharge.ResultsNine clinical studies met the inclusion criteria. The studies’ results indicate that there may be a relationship between abnormal HRV and clinical depression when assessed early after an ACS event, offering the possibility that these risk factors play a modest role in patient outcomes.ConclusionWhile a definitive conclusion about the relevance of HRV and clinical depression measurement in ACS patients would be premature, the literature suggests that these measures may provide additional information in risk assessment. Potential avenues for further research are proposed.

show abstract

“…Since the initial report of Wolf et al (1978) of the relationship of decreased RR variability on ECG and morality in post-MI patients, different methodologies have been developed and are now available to measure HRV in the experimental laboratory and in the clinical setting (Malik and Camm, 1995; Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology, 1996). These range from simple statistical descriptors to complex non-linear mathematical parameters.…”

Section: Heart Rate Variabilitymentioning

confidence: 99%

Origin of Heart Rate Variability and Turbulence: An Appraisal of Autonomic Modulation of Cardiovascular Function

Lombardi¹,

Stein²

2011

Front. Physio.

123

114

View full text Add to dashboard Cite

Heart period constantly changes on a beat to beat basis, due to autonomic influences on the sinoatrial node, and changes can be quantified as heart rate variability (HRV). In addition, after a premature ventricular beat, there are reproducible variations in RR interval, also due to baroreflex mediated autonomic influences on the sinoatrial node, that can be measured as heart rate turbulence (HRT). Impaired autonomic function as measured by HRV and HRT has proven to predict adverse outcomes in clinical settings. The ability of reduced HRV and HRT to predict adverse outcomes has been explained by their dependency on vagal mechanisms that could reflect an increased sympathetic and a reduced vagal modulation of sinus node, thus favoring cardiac electrical instability. Analysis of non-linear dynamics of HRV has also been utilized to describe the fractal like characteristic of the variability signal and proven effective in identify patients at risk for sudden cardiac death. Despite the clinical validity of these measures, it has also been evident that the relationship between neural input and sinus node responsiveness is extremely complex and variable in different clinical conditions. Thus, abnormal HRV or HRT on a clinical Holter recordings may reflect non-neural as well as autonomic mechanisms, and this also needs to be taken into account when interpreting any findings. However, under controlled conditions, the computation of the low and high frequency components of HRV and of their normalized powers or ratio seems capable of providing valid information on sympatho-vagal balance in normal subjects, as well as in most patients with a preserved left ventricular function. Thus, analysis of HRV does provide a unique tool to specifically assess autonomic control mechanisms in association with various perturbations. In conclusion, HRV measures are of substantial utility to identify patients with an increased cardiac mortality and to evaluate autonomic control mechanisms, but their ability to capture specific levels of autonomic control may be limited to controlled laboratory studies in relatively healthy subjects.

show abstract

Sinus Arrhythmia in Acute Myocardial Infarction

Cited by 382 publications

References 2 publications

Heart rate variability in children with aortic valve stenosis – a pilot study

Heart rate variability in children with aortic valve stenosis – a pilot study

Heart rate variability measurement and clinical depression in acute coronary syndrome patients: narrative review of recent literature

Origin of Heart Rate Variability and Turbulence: An Appraisal of Autonomic Modulation of Cardiovascular Function

Contact Info

Product

Resources

About