Sinus Node Dysfunction

Sathnur, Neeraj; Ebin, Emanuel; Benditt, David G.

doi:10.1016/j.ccep.2021.06.006

Cited by 7 publications

(2 citation statements)

References 96 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To the best of our knowledge from a review of the literature, the patient we described is the first case of VV-ECMO cannula-induced sinus bradycardia, but similar findings have been reported with other forms of mechanical manipulation around the carotid sinus. While syncope is not a concern for sedated patients, bradyarrhythmia has been shown to increase the risk of thromboembolic complications [ 4 ]. Several cases of episodic sinus bradycardia have been observed in laryngoscopic procedures, laryngeal mask airway placements, and invasive squamous cell carcinoma including cases of reproducible bradycardic pauses [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

Extracorporeal Membrane Oxygenation (ECMO) Cannula Stimulation of the Carotid Sinus Causing Bradycardic Pauses in a Patient With COVID-19

Dayco¹,

Pawloski²,

Sokolowski³

et al. 2023

Cureus

View full text Add to dashboard Cite

Veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannulation is a potential cause of episodic bradycardia during an intensive care course because of the proximal cannula insertion site being in the vicinity of the carotid sinus. Herein, we report the case of episodic bradycardia throughout a multi-week intensive care stay of a VV-ECMO recipient due to a severe coronavirus disease 2019 (COVID-19) infection that did not emerge for the rest of the patient's hospitalization after decannulation.

show abstract

Section: Discussionmentioning

confidence: 99%

Extracorporeal Membrane Oxygenation (ECMO) Cannula Stimulation of the Carotid Sinus Causing Bradycardic Pauses in a Patient With COVID-19

Dayco¹,

Pawloski²,

Sokolowski³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…A commonly used form of SNRT is the corrected SNRT (cSNRT), which is obtained by subtracting the baseline sinus cycle length from the SNRT; the value of cSNRT in normal adult ranges from 500 to 550 ms (most commonly <525 ms) ( Sathnur et al, 2021 ). Some reports have demonstrated excellent success in the group with abnormal cSNRT ( Aksu et al, 2020 ; Aksu et al, 2021 ), although cSNRT over 525 ms (considered a positive indication of intrinsic changes of the sinus node) was used as an exclusion criterion in two purely SND studies ( Zhao et al, 2015 ; Qin et al, 2017 ).…”

Section: Selection Criteria For Patients Undergoing Cardioneuroablati...mentioning

confidence: 99%

Selection of patients with symptomatic vagal-induced sinus node dysfunction: Who will be the best candidate for cardioneuroablation?

2023

View full text Add to dashboard Cite

Sinus node dysfunction is a multifaceted disorder with variable manifestations, the prevalence of which increases with age. In a specific group of patients, excessive vagal activity may be the sole cause for this condition. These patients are characterized as having recurrent daytime symptoms attributed to bradyarrhythmia, no evidence of organic sinus node lesions, cardiac vagal overactivation, and are non-elderly. For sinus node dysfunction patients, a permanent pacemaker implantation appears to be the ultimate solution, although it is not an etiological treatment. Cardioneuroablation is a promising emerging therapy that can fundamentally eliminate symptoms in a highly selective sub-set of sinus node dysfunction patients by cardiac vagal nerve denervation. Denervation with ablation for vagal-induced sinus node dysfunction can effectively improve sinus bradycardia and reduce syncope. To date, guidelines for selection of suitable candidates for cardioneuroablation remain lacking. The primary objective of this study was to distinguish the nature of abnormal sinus node function and to find methods for quantifying vagal tone. Clear selection criteria could help physicians in identification of patients with autonomic imbalance, thereby maximizing patient benefits and the success rate of cardioneuroablations.

show abstract

Risks and Consequences

Ostrom¹,

Wilhelmsen²

2012

Risk Assessment

View full text Add to dashboard Cite

Sinus Node Dysfunction

Cited by 7 publications

References 96 publications

Extracorporeal Membrane Oxygenation (ECMO) Cannula Stimulation of the Carotid Sinus Causing Bradycardic Pauses in a Patient With COVID-19

Extracorporeal Membrane Oxygenation (ECMO) Cannula Stimulation of the Carotid Sinus Causing Bradycardic Pauses in a Patient With COVID-19

Selection of patients with symptomatic vagal-induced sinus node dysfunction: Who will be the best candidate for cardioneuroablation?

Risks and Consequences

Contact Info

Product

Resources

About