The rampant influence of technology certainly has positive and negative impacts on the increasingly complex development of health sciences and diseases. Technology in the field of computerization has been widely used in various lines of life. Technology is very helpful in various aspects of life, with the existence of technology humans can create various tools to facilitate human work. Cerebral Palsy is a disease or disorder that often occurs in today's development. Cerebral Palsy is not a fatal disease but a condition that affects the body, its treatment and treatment can help regulate its effects on the body. An expert system is a system that adopts human knowledge to a computer that combines basic knowledge with an inference system to replace the function of an expert in solving a problem. advances in expert systems can overcome this problem by designing a Desktop-based computer system that uses the Java programming language and MySQL database so that it can help users to diagnose disease. Various methods can be used to build expert systems, one of which is the Case Based Reasoning method. Where the process of calculating Case Based Reasoning compares new cases with old cases and divides them into four stages, namely retrieve, reuse, revise and retain, to get the results of the type of disease suffered by the patient in the form of a percentage. In this expert system, the system will ask questions like a patient is having a dialogue with an expert. Then, select yes for symptoms that are felt and no for symptoms that are not felt. The system will make a diagnosis based on the patient's symptoms. Diagnostic results include the type of Cerebral Palsy experienced and treatment options as well as the percentage of patients likely to suffer from the disease