Sistemik Skleroz’da Özofagus Tutulumu ve Gastroözofageal Reflü Hastalığı: Üçüncü Basamak Deneyimi

Abstract

In this study, we investigated the demographic features, endoscopic, manometric, and 24-hour pH monitoring findings of patients with SS. Materials and Method:Twenty-six patients with SS who presented with dysphagia or heartburn complaints were identified. Patients' files, endoscopic, manometric, and 24-hour ph monitoring findings of the esophagus were examined.Results: All of the patients were symptomatic. The average age of 26 patients was 47.9 years and 96% were women. 46.1% of them applied with the complaint of heartburn and 53.9% with the complaint of dysphagia. The frequency of esophagitis in patients with SS was found to be significantly higher (p=0.005). Pathological reflux was detected in 90% of the patients with SS who underwent 24-hour pH monitoring and it was significantly higher (p=0.013). The mean esophageal body resting pressure in the patient with SS group was -0.73 mmHg and was significantly lower than that of control group (p<0.001). The mean resting LES pressure in the patient with SS group was 3.3 mmHg and was significantly lower than that of control group (p=0.028). Conclusion:Esophageal involvement is a hallmark manifestation of SS and typically occurs secondary to heartburn and dysphagia. In our society, the incidence of Gastroesophageal Reflux Disease (GERD) and GERD-related complications is high in SS patients with esophageal symptoms. It is important to refer these patients to experienced gastroenterology centers to be evaluated by endoscopic and then other diagnostic methods.