In the frame of a Belgo-Haitian cooperation project (PIC 2012–2016), a study of the local seismic hazard was performed in Fond Parisien, an area located on the foothills of the “Massif de la Selle”, along the easternmost portion of the Enriquillo Plantain Garden Fault (EPGF). The H/V Spectral Ratio (HVSR) technique was applied to study the resonance frequency of the target areas and the azimuth of the wave field. The amplification factors were estimated using Standard Spectral Ratios obtained from earthquakes recorded by a temporary seismic network. Using the Multichannel Analysis of Surface Waves method, the seismic properties of the shallow layers were investigated. Then, the results were compared to local Electrical Resistivity Tomography data. These results highlight, in the central part of Fond Parisien, an E-W zone of low velocities ranging from 200 m/s to 450 m/s and low resistivities between 1 Ωm and 150 Ωm, due both to tectonic folding of the rocks and to the presence of sediment filling in the eastern part. The latter is marked, in most of its sites, by resonances at one or more frequencies ranging from 0.7 Hz to 20 Hz. Infiltration and storage of brackish water in the underground layers also contribute to the low resistivity values. With the noise HVSR data, we also evidenced a significant influence of the EPGF on the main orientation of the seismic wavefield as in the vicinity of this fault, the azimuths are parallel to the orientation of the fault. Overall, the results also show greater potential for site effects in the block formed by the sedimentary basin and strong amplification of the seismic ground motion for the sites bordering the basin to the north and west. We interpret the amplification in the north and south-west as probably originating from topographic irregularities locally coupled with sediment deposits, while in the center of the western part, the site effects could be explained by the presence of folds and related weakened and softened rocks. By the integration of several geophysical methods, we could distinguish areas where it is possible to build more safely. These zones are located in the northern part and encompass Quisqueya Park and neighboring areas as well as the village “La Source” in the southern part. In the rest of Fond Parisien, i.e., in the more central and eastern parts, buildings should be erected with caution, taking into account the nearby presence of the EPGF and the influence of fine sediments on the amplification of the seismic motion.