2005
DOI: 10.1007/s00383-005-1412-y
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Situs inversus abdominus in association with congenital duodenal obstruction: a report of two cases and review of the literature

Abstract: This report describes two newborns with persistent bile-stained vomiting. Their radiological investigations revealed the existence of situs inversus and duodenal obstruction. In one, the duodenal obstruction was partial, secondary to a duodenal diaphragm with a central aperture, whereas the other child had complete duodenal atresia as well as Fallot's tetralogy. Such an association is extremely rare, with only 18 cases reported so far in the literature. Embryological aspects, investigations, and treatment are … Show more

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Cited by 37 publications
(40 citation statements)
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“…Dextrocardia with situs inversus is a rare condition occurring in about one per 10,000 in the general population 3 There is no racial predilection for situs inversus and the male-to-female incidence is 1:1. This anomaly may not be diagnosed until late in life in some cases and it is associated with primary ciliary dyskinesia and splenic malformations in some individuals 3 The arrangements of the position of the abdominal viscera in dextrocardia may be normal (situs solitus), reversed (situs inversus), and indeterminate (situs ambiguous or isomerism) in 32-35%, 35-39% and 26-28% of cases respectively 4 Though the exact cause is unknown, dextrocardia has been linked with a number of factors including autosomal recessive gene with incomplete penetrance, maternal diabetes, cocaine use and conjoined twinning.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Dextrocardia with situs inversus is a rare condition occurring in about one per 10,000 in the general population 3 There is no racial predilection for situs inversus and the male-to-female incidence is 1:1. This anomaly may not be diagnosed until late in life in some cases and it is associated with primary ciliary dyskinesia and splenic malformations in some individuals 3 The arrangements of the position of the abdominal viscera in dextrocardia may be normal (situs solitus), reversed (situs inversus), and indeterminate (situs ambiguous or isomerism) in 32-35%, 35-39% and 26-28% of cases respectively 4 Though the exact cause is unknown, dextrocardia has been linked with a number of factors including autosomal recessive gene with incomplete penetrance, maternal diabetes, cocaine use and conjoined twinning.…”
Section: Discussionmentioning
confidence: 99%
“…This anomaly may not be diagnosed until late in life in some cases and it is associated with primary ciliary dyskinesia and splenic malformations in some individuals 3 The arrangements of the position of the abdominal viscera in dextrocardia may be normal (situs solitus), reversed (situs inversus), and indeterminate (situs ambiguous or isomerism) in 32-35%, 35-39% and 26-28% of cases respectively 4 Though the exact cause is unknown, dextrocardia has been linked with a number of factors including autosomal recessive gene with incomplete penetrance, maternal diabetes, cocaine use and conjoined twinning. 5,6 The mechanism responsible for malrotation of intestinal loops is yet to be understood.…”
Section: Discussionmentioning
confidence: 99%
“…1 This anomaly may not be diagnosed until late life in some cases and it is associated with primary ciliary dyskinesia and splenic malformations. 3 It has been shown that the incidence of congenital heart malformations is higher in patients with dextrocardia and situs inversus than in patients with normal situs solitus. 2 This is due to the fact that dextrocardia with situs inversus is merely a mirror image of the normal situs solitus, 2 hence any associated cardiac malformations are usually mirror images of similar malformations in people with the normal situs solitus.…”
Section: Discussionmentioning
confidence: 99%
“…Individuals with dextrocardia and situs inversus totalis may have associated congenital heart malformations 2 , primary ciliary dyskinesia or splenic malformations. 3 We describe a case of dextrocardia with situs inversus totalis in a one day old neonate with neonatal sepsis, the first case to be reported in Gusau, Zamfara State, Nigeria.…”
Section: Introductionmentioning
confidence: 94%
“…The male to female ratio is 1:1 and there is no racial predilection. 12,13 It is characterized by the transposition of the major thoracic organs and all the visceral organs of the abdomen to opposite side of normal position in the body. The stomach and the spleen are on the right, while the liver and gall bladder are located on the left.…”
mentioning
confidence: 99%