Situs inversus totalis: revisión de tema con aproximación a la Genética y reporte de casos

Reales, Vicente de Jesús Aljure; Gallego, Gloria Camila Álvarez; Espitia, Nasly Consuelo Ávila; Coley, A. A. M.

doi:10.1016/j.rccar.2016.06.016

Cited by 7 publications

(13 citation statements)

References 27 publications

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“…[2] Classically, situs inversus totalis is asymptomatic, although a third of the cases are associated with a recessive genetic condition: primary ciliary dyskinesia. [2] Other concomitant pathologies are increasingly being reported, including: cardiovascular malformations (tetralogy of Fallot, pulmonary stenosis, defects in the development of the atrial or ventricular septum), lung adenocarcinoma, metastasis of gallbladder carcinoma, and biliary atresia. [2,3] The pathogenesis of SIT is still not well established.…”

Section: Introductionmentioning

confidence: 99%

“…[4] In addition, it tends to occur commonly in men (1.5:1) and there is no racial predilection. [2,4] The objective of this study was to know the characteristics of SIT and its relationship with different types of cancer of the abdominopelvic region.…”

Section: Introductionmentioning

confidence: 99%

“…[2] Other concomitant pathologies are increasingly being reported, including: cardiovascular malformations (tetralogy of Fallot, pulmonary stenosis, defects in the development of the atrial or ventricular septum), lung adenocarcinoma, metastasis of gallbladder carcinoma, and biliary atresia. [2,3] The pathogenesis of SIT is still not well established. The involvement of an autosomal recessive gene on the long arm of chromosome 14 and deletions on chromosomes 7 and 8 have been established.…”

Section: Introductionmentioning

confidence: 99%

“…The involvement of an autosomal recessive gene on the long arm of chromosome 14 and deletions on chromosomes 7 and 8 have been established. [2] The correlation with deletions of KIF3-A and KIF3-B, 2 microtubule-dependent motor kinesins involved in cancer development, and whose nonfunctional forms prevent the transport of the cell adhesion factors N-cadherin and β-catenin to the cell surface has also been studied. [4] The epidemiology of these anatomical variations differs according to the literature.…”

Section: Introductionmentioning

confidence: 99%

“…[4] In addition, it tends to occur commonly in men (1.5:1) and there is no racial predilection. [2,4]…”

Section: Introductionmentioning

confidence: 99%

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Association between types of abdominopelvic cancer in patients with situs inversus total: Systematic review

Valenzuela-Fuenzalida,

Martínez Hernández,

Milos-Brandenberg

et al. 2024

Medicine

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Background: Situs inversus is a rare congenital anatomical variant that involves a group of anomalies regarding the arrangement of intrathoracic and intraabdominal organs. Being able to find in the abdominal region the liver, gallbladder, inferior vena cava, and head of the pancreas and ascending colon on the left side of the abdomen, while on the right side there is the spleen, the stomach, the body of the pancreas, the ligament of Treitz, descending colon among others. In this same way, the thoracic organs, lungs and heart, are changed in their position in a mirror translocation. Methods: We systematically searched MEDLINE, Web of Science, Google Scholar, CINAHL, Scopus, and LILACS; the search strategy included a combination of the following terms: “Situs inversus,” “Situs inversus totalis,” “Cancer,” “Neoplasm,” “Abdominopelvic regions,” and “clinical anatomy.” Results: Within the 41 included studies, 46 patients with situs inversus who had cancer, in addition to being found in this organ and in these regions, we also found as a result that the majority of the studies in the research were in stage II; finally, no one study could assert the direct relationship between the situs inversus totalis and the cancer. Conclusion: If our hallmarks could make us think that more exhaustive follow-up of the stomach and other organs should be carried out in these patients, there could also be other predisposing factors for cancer, which is why more studies are suggested to give future diagnostic and treatment guidelines treatment.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…[4] In addition, it tends to occur commonly in men (1.5:1) and there is no racial predilection. [2,4]…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Association between types of abdominopelvic cancer in patients with situs inversus total: Systematic review

Valenzuela-Fuenzalida,

Martínez Hernández,

Milos-Brandenberg

et al. 2024

Medicine

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Imaging evaluation of the heterotaxy syndrome

Garrido¹,

Jerez²,

Hernández³

et al. 2019

GHOA

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Situs ambiguus, or heterotaxy, is a rare syndrome characterized by an abnormal arrangement of the internal organs in the chest and abdomen and is usually associated with congenital heart diseases. Despite its variable presentation, heterotaxy syndrome can be classified into heterotaxy with polysplenia or left isomerism, and heterotaxy with asplenia or right isomerism. The different imaging techniques reveal the characteristic imaging findings that allow an accurate description of each patient's specific anatomy. Evaluation of the position of the following structures relative to midline is crucial: atria, cardiac apex, venous drainage, aorta, stomach, liver and gallbladder, as well as the presence or absence of intestinal malrotation, number of spleens, and presence of tri-or bilobed lungs. We present a case report of a 42-year-old man with dextrocardia underwent laparoscopic cholecystectomy for cholelithiasis. Subsequently, a complete resection of the common bile duct required reconstruction of the biliary tract. During six years the patient underwent frequent examinations for recurrent episodes of cholangitis that required stenosis dilation and biliary stent placement using endoscopic retrograde cholangiopancreatography. Despite these treatments, the patient required surgery again for biliary stenosis, this time a bilioenteric anastomosis (Roux-en-Y) was performed. During the surgical procedure migration of the biliary stent occurred.

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Manejo anestésico para exéresis de glioma temporal en un paciente con <i>situs inversus</i>. Reporte de caso

Arévalo-Gutiérrez

2023

RECC

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Los tumores cerebrales primarios malignos son los más difíciles de tratar, con una supervivencia a 5 años no superior al 35%. Los más comunes en adultos son los gliomas. El situs inversus totalis es una condición rara, con una incidencia de 1 en 20,000 entre la población general, cuyos factores etiológicos no se conocen por completo. Durante un procedimiento neuroquirúrgico, el manejo anestésico es desafiante. Se reporta el caso de una paciente que presenta situs inversus totalis, con una comunicación interventricular moderada e hipertensión pulmonar grave, a quien se le realizó exéresis de un glioma temporal derecho. La inducción anestésica se realizó con propofol 2 mg/kg y remifentanilo 4 ng/ml, besilato de cisatracurio 10 mg, índice biespectral de 40 e intubación orotraqueal satisfactoria. El mantenimiento se estableció mediante anestesia total intravenosa con propofol 5 mg/kg/h y remifentanilo 5 ng/ml. Estable hemodinámicamente en el transquirúrgico, con presiones arteriales medias de 80-90 mmHg, saturaciones de oxígeno del 90-92%, CO 2 espirado de 32-35 mmHg, sin uso de vasopresores ni transfusiones sanguíneas. Con evolución cardíaca y neurológica satisfactoria, fue dada de alta en su cuarto día posquirúrgico, con adecuada deambulación y Glasgow de 15 puntos.Palabras clave: Anestesia general. Tumores primarios malignos del cerebro. Situs inversus. Posición prona y sentado. Monitoreo intraoperatorio.

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Situs inversus totalis: revisión de tema con aproximación a la Genética y reporte de casos

Cited by 7 publications

References 27 publications

Association between types of abdominopelvic cancer in patients with situs inversus total: Systematic review

Association between types of abdominopelvic cancer in patients with situs inversus total: Systematic review

Imaging evaluation of the heterotaxy syndrome

Manejo anestésico para exéresis de glioma temporal en un paciente con <i>situs inversus</i>. Reporte de caso

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