Six Minute Walk Test: A Tool for Predicting Mortality in Chronic Pulmonary Diseases

Karanth, Mp Swathi; Awad, Nilkanth Tukaram

doi:10.7860/jcdr/2017/24707.9723

Cited by 16 publications

(17 citation statements)

References 29 publications

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“…In the absence of traditional lung function equipment and pulmonary spirometry, we decided to measure the patient’s functional status by a 6MWT. A study in India attested to its simplicity and value in predicting mortality in patients with chronic lung disease [ 33 ]. The Indian study included 31 patients with post-TB sequelae: in those patients, the 6MWT showed a median of 192 m walked (range 48–383) in those who subsequently died compared with a median of 335 m walked (range 136–585) in those who survived [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

“…A study in India attested to its simplicity and value in predicting mortality in patients with chronic lung disease [ 33 ]. The Indian study included 31 patients with post-TB sequelae: in those patients, the 6MWT showed a median of 192 m walked (range 48–383) in those who subsequently died compared with a median of 335 m walked (range 136–585) in those who survived [ 33 ]. In other post-TB studies, the 6MWT has been used to assess functional status, and in Benin about 40% of the patients had an abnormal 6MWT below the lower limit of normal for their age [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

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Is It Feasible to Conduct Post-Tuberculosis Assessments at the End of Tuberculosis Treatment under Routine Programmatic Conditions in China?

Lin

Liu²,

Zhang

et al. 2021

TropicalMed

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There is growing evidence that a substantial proportion of people who complete anti-tuberculosis treatment experience significant morbidity and mortality which can negatively affect their quality of life. It is suggested that national tuberculosis programs conduct end-of-treatment assessments, but whether this is feasible is currently not known. We therefore assessed whether tuberculosis program staff could assess functional and general health status of patients at the end of treatment in five TB clinics in four provinces in China. There were 115 patients, aged 14–82 years, who completed anti-tuberculosis treatment and a post-TB assessment. There were 54 (47%) patients who continued to have symptoms, the commonest being cough, dyspnea and fatigue. Symptom continuation was significantly more common in the 22 patients with diabetes (p = 0.027) and the 12 patients previously treated for TB (p = 0.008). There were 12 (10%) current smokers, an abnormal chest X-ray was found in 106 (92%) patients and distance walked in the 6-min walking test (6MWT) ranged from 30–750 m (mean 452 ± 120); 24 (21%) patients walked less than 400 m. Time taken to perform the post-TB assessment, including the 6MWT, ranged from 8–45 min (mean 21 ± 8 min). In 98% of the completed questionnaires, health workers stated that conducting post-TB assessments was feasible and useful. This study shows that post-TB assessments can be conducted under routine programmatic conditions and that there is significant morbidity that needs to be addressed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Is It Feasible to Conduct Post-Tuberculosis Assessments at the End of Tuberculosis Treatment under Routine Programmatic Conditions in China?

Lin

Liu²,

Zhang

et al. 2021

TropicalMed

View full text Add to dashboard Cite

show abstract

“…The 6MWT was originally developed for assessing exercise capacity in patients with cardiopulmonary diseases [2]. However, it has also been commonly used to measure functional status [3,4], as a predictor of morbidity and mortality [5,6], and for pre/post-treatment comparisons [7,8]. Besides the 6MWD, other useful outcome measures may be extracted from the 6MWT, including pulmonary function metrics [9], patient-reported fatigue at the beginning and end of the test using the Borg scale [10], and 6MWT work, calculated as the product of 6MWD and body weight [11].…”

Section: Introductionmentioning

confidence: 99%

Wearable Inertial Sensors to Assess Gait during the 6-Minute Walk Test: A Systematic Review

Storm

Cesareo

Reni

et al. 2020

Sensors

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Wearable sensors are becoming increasingly popular for complementing classical clinical assessments of gait deficits. The aim of this review is to examine the existing knowledge by systematically reviewing a large number of papers focusing on the use of wearable inertial sensors for the assessment of gait during the 6-minute walk test (6MWT), a widely recognized, simple, non-invasive, low-cost and reproducible exercise test. After a systematic search on PubMed and Scopus databases, two raters evaluated the quality of 28 full-text articles. Then, the available knowledge was summarized regarding study design, subjects enrolled (number of patients and pathological condition, if any, age, male/female ratio), sensor characteristics (type, number, sampling frequency, range) and body placement, 6MWT protocol and extracted parameters. Results were critically discussed to suggest future directions for the use of inertial sensor devices in the clinics.

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“…Moreover, it is considered to be more representative of the patients’ daily activity, when compared to other field or cardiopulmonary exercise tests 104 . A reduced 6MWT distance is an adequate index of functional disability and an increased mortality risk, although no predictions can be made regarding hospitalizations due to COPD exacerbations 103 , 105 . As a result, 6MWT has been tested and included in the Body mass index, Obstruction, Dyspnea, and Exercise capacity (BODE) index 106 .…”

Section: Introductionmentioning

confidence: 99%

Pulmonary function testing in COPD: looking beyond the curtain of FEV1

Kakavas

Kotsiou

Perlikos

et al. 2021

npj Prim. Care Respir. Med.

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Chronic obstructive pulmonary disease (COPD) management remains challenging due to the high heterogeneity of clinical symptoms and the complex pathophysiological basis of the disease. Airflow limitation, diagnosed by spirometry, remains the cornerstone of the diagnosis. However, the calculation of the forced expiratory volume in the first second (FEV1) alone, has limitations in uncovering the underlying complexity of the disease. Incorporating additional pulmonary function tests (PFTs) in the everyday clinical evaluation of COPD patients, like resting volume, capacity and airway resistance measurements, diffusion capacity measurements, forced oscillation technique, field and cardiopulmonary exercise testing and muscle strength evaluation, may prove essential in tailoring medical management to meet the needs of such a heterogeneous patient population. We aimed to provide a comprehensive overview of the available PFTs, which can be incorporated into the primary care physician’s practice to enhance the efficiency of COPD management.

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Six Minute Walk Test: A Tool for Predicting Mortality in Chronic Pulmonary Diseases

Cited by 16 publications

References 29 publications

Is It Feasible to Conduct Post-Tuberculosis Assessments at the End of Tuberculosis Treatment under Routine Programmatic Conditions in China?

Is It Feasible to Conduct Post-Tuberculosis Assessments at the End of Tuberculosis Treatment under Routine Programmatic Conditions in China?

Wearable Inertial Sensors to Assess Gait during the 6-Minute Walk Test: A Systematic Review

Pulmonary function testing in COPD: looking beyond the curtain of FEV1

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