Six-month follow-up of functional status in discharged patients with coronavirus disease 2019

Background Acute COVID-19 clinical symptoms have been clearly documented, but long-term functional and symptomatic recovery from COVID -19 is less well described. Methods A systematic review and meta-analysis were conducted to describe patient-reported outcome measures (PROMs) in adults at least 8 weeks post hospital discharge for COVID-19. Comprehensive database searches in accordance with the PRISMA statement were carried out up till 31/05/2021. Data were narratively synthesized, and a series of meta-analyses were performed using the random-effects inverse variance method. Results From 49 studies, across 14 countries with between 2-12 months follow up, the most common persisting symptom reported was fatigue with meta-analysis finding 36.6% (95 % CI 27.6 to 46.6, n=14) reporting it at 2-4 months, decreasing slightly to 32.5% still reporting it at >4 months (95% CI 22.6 to 44.2, n=15). This was followed by dyspnoea. Modified MRC score (mMRC) ≥1 was reported in 48% (95% CI 30 to 37, n=5) at 2-4months reducing to 32% (95% CI 22 to 43, n=7) at 4 months. Quality of life (QOL) as assessed by the EQ-5D-5L VAS remained reduced at >4 months (73.6 95% CI 68.1 to 79.1, n=6). Hospitalisation with COVID-19 also resulted in persisting sick leave, change in scope of work, and continued use of primary and secondary healthcare. Conclusion The symptomatic and functional impact of COVID-19 continues to be felt by patients months after discharge from hospital. This widespread morbidity points towards a multi-disciplinary approach to aid functional recovery.

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Functional Capacity and Self-Care in Post-COVID-19 Patients in a Recovery Program

Góis,

Rodrigues,

Teles

2024

Aquichan

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Introduction: COVID-19 manifests with acute symptoms. After coronavirus infection, they may persist or new ones may emerge, compromising functional capacity and self-care. This condition has been named “acute post-COVID-19 syndrome”. Objective: To evaluate functional capacity and self-care in post-COVID-19 patients. Materials and methods: This is a descriptive and exploratory study, which evaluated 53 medical records of patients receiving care in a Functional Recovery Program for acute post-COVID-19 syndrome, conducted at a public university, from August 2022 to August 2023. A descriptive and association analysis was performed using Pearson’s Chi-squared or Fisher’s exact nonparametric tests, with a significance level of 5 % (p < 0.05). Results: Most participants were female, aged over 50 and receiving home care during the infection. Associations were found between the length of hospitalization (p = 0.03), having a history of surgery (p = 0.01), and a medium self-care capacity (p = 0.04) with the functional capacity to perform instrumental activities of daily living (IADL). Conclusion: Post-COVID-19 syndrome is associated with medium self-care capacity and partial dependence in terms of IADLs. The finding contributes to the development of health education and care strategies aimed at providing recovery.

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Six-month follow-up of functional status in discharged patients with coronavirus disease 2019

Cited by 3 publications

References 26 publications

Post Pulmonary Embolism Syndrome

Post Pulmonary Embolism Syndrome

Patient-reported respiratory outcome measures in the recovery of adults hospitalised with COVID-19: A systematic review and meta-analysis

Functional Capacity and Self-Care in Post-COVID-19 Patients in a Recovery Program

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