Six-Month Outcome following a Relapse of Schizophrenia

Bergen, Jenny; Hunt, Glenn E.; Armitage, Paul A.; Bashir, Marie

doi:10.3109/00048679809073871

Cited by 54 publications

(36 citation statements)

References 29 publications

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“…Furthermore, though the findings indicate that nearly 60% of children and adolescents will relapse, the relapse rates decrease over time providing hope for families where relapse has not yet occurred. Contrary to studies involving adults (Bergen et al, 1998;Favre et al, 1997), most of youth participating in this study were medication adherent. Importantly, among those who were adherent, there was a decreased likelihood of readmission.…”

Section: Discussioncontrasting

confidence: 73%

“…Similar to the adult population (Bergen et al, 1998;Giron and GomezBeneyto, 1995;Hunt et al, 2002;Muller, 2004;Parker and HadziPavlovic, 1995;Robinson et al, 1999a;Sullivan et al, 1995), nonadherence to medication was a strong predictor of relapse. Children and adolescents who were adherent to medication had one third (HR ϭ 0.331; 95% CI, 0.18 -0.61; p ϭ 0.0004) the hazard of relapse as youth who were not adherent.…”

Section: As Shown Inmentioning

confidence: 85%

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Developing a Risk-Model of Time to First-Relapse for Children and Adolescents With a Psychotic Disorder

Gearing

Mian²,

Sholonsky³

et al. 2009

Journal of Nervous &Amp; Mental Disease

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Individuals treated for psychotic disorders and mood disorders with psychotic features have a high likelihood of relapse across the life course. This study examines the relapse rate and its associated predictors for children and adolescents experiencing a first-episode and develops a statistical risk-model for prediction of time to first-relapse. A multiyear, retrospective cohort design was used to track youth, under the age of 18 years, who experienced a first-episode of psychosis, and were admitted to 1 of 6 inpatient hospital psychiatric units (N = 87). Participants were followed for at least 2 years (M = 3.9, SD = 1.3) using survival analysis. Approximately 60% of subjects experienced relapse requiring hospital readmission by the end of follow-up, with 33% readmitted within the first year and 44% within 2 years. Median survival time was 34 months. Cox proportional hazards regression identified 4 key risk factors for relapse: medication nonadherence, female gender, receiving clinical treatment, and a decline in social support before first admission.

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Section: Discussioncontrasting

confidence: 73%

Section: As Shown Inmentioning

confidence: 85%

Developing a Risk-Model of Time to First-Relapse for Children and Adolescents With a Psychotic Disorder

Gearing

Mian²,

Sholonsky³

et al. 2009

Journal of Nervous &Amp; Mental Disease

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“…When the member with the mental disorder is the household head, factors associated with municipal services may act to increase the stress on this person. This has been associated with increased rates of relapse (Bergen et al 1998). …”

Section: Discussionmentioning

confidence: 98%

Experience of mental disorder in the context of basic service reforms: The impact on caregiving environments in South Africa

Breen

Swartz

Flisher

et al. 2007

International Journal of Environmental Health Research

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The integration of mental health services into primary health care and the shift towards community- and family-based care for chronic mental disorders has been associated with increased burden on households. At the same time, research investigating the impact of policies of cost recovery for basic services such as water and electricity has also indicated an increased burden on households. This study aimed to investigate the impact of these basic service reforms on households caring for a family member with a chronic mental disorder in Cape Town, South Africa. The findings indicate that factors associated with service reforms may increase the stress and burden experienced by households and in turn impact on the primary environment in which care is received.

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“…Persons who have both a mental illness and a substance use disorder appear to have the highest risk of poor adherence; studies have usually shown a strong association between substance use and nonadherence (2)(3)(4)(5)(6)(7)(8), although some studies have shown no relationship (9,10).…”

mentioning

confidence: 99%

Adherence to Medication Regimens and Participation in Dual-Focus Self-Help Groups

Magura¹,

Laudet²,

Mahmood³

et al. 2002

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Objective-The authors examined the associations between attendance at self-help meetings, adherence to psychiatric medication regimens, and mental health outcomes among members of a 12-step self-help organization specifically designed for persons with both chronic mental illness and a substance use disorder.Methods-A sample of members of Double Trouble in Recovery (DTR) was interviewed at baseline and one year later. Correlates of adherence to psychiatric medication regimens at the followup interview were identified for 240 attendees who had received a prescription for a psychiatric medication.Results-Consistent attendance at DTR meetings was associated with better adherence to medication regimens after baseline variables that were independently associated with adherence were controlled for. Three baseline variables were associated with adherence: living in supported housing, having fewer stressful life events, and having a lower severity of psychiatric symptoms. In addition, better adherence was associated with a lower severity of symptoms at one year and no psychiatric hospitalization during the follow-up period.Conclusions-Treatment programs and clinicians should encourage patients who have both mental illness and a substance use disorder to participate in dual-focus self-help groups that encourage the responsible use of effective psychiatric medication, particularly after discharge to community living. Clinicians also should be sensitive to stressful life events and discuss with patients how such events might affect their motivation or ability to continue taking medication.Poor adherence to psychiatric medication regimens is a major obstacle to the effective care of persons who have chronic mental illness. A recent review reported that patients who were receiving antipsychotics or antidepressants took an average of 58 percent and 65 percent,

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Six-Month Outcome following a Relapse of Schizophrenia

Cited by 54 publications

References 29 publications

Developing a Risk-Model of Time to First-Relapse for Children and Adolescents With a Psychotic Disorder

Developing a Risk-Model of Time to First-Relapse for Children and Adolescents With a Psychotic Disorder

Experience of mental disorder in the context of basic service reforms: The impact on caregiving environments in South Africa

Adherence to Medication Regimens and Participation in Dual-Focus Self-Help Groups

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