Size characterisation of Au nanoparticles by ICP-MS coupling techniques

Helfrich, Andreas; Brüchert, Wolfram; Bettmer, Jörg

doi:10.1039/b511705d

Cited by 97 publications

(58 citation statements)

References 20 publications

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“…More recently, Helfrich et al [130] proposed size characterisation of Au NPs by on-line coupling of liquid chromatography, or alternatively gel electrophoresis, with ICP-MS, as shown in Fig. 7.…”

Section: Separation Techniques Coupled With Inductively Coupled Plasmmentioning

confidence: 99%

Inorganic mass spectrometry as a tool for characterisation at the nanoscale

et al. 2009

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Inorganic mass spectrometry techniques may offer great potential for the characterisation at the nanoscale, because they provide unique elemental information of great value for a better understanding of processes occurring at nanometre-length dimensions. Two main groups of techniques are reviewed: those allowing direct solid analysis with spatial resolution capabilities, i.e. lateral (imaging) and/or indepth profile, and those for the analysis of liquids containing colloids. In this context, the present capabilities of widespread elemental mass spectrometry techniques such as laser ablation coupled with inductively coupled plasma mass spectrometry (ICP-MS), glow discharge mass spectrometry and secondary ion/neutral mass spectrometry are described and compared through selected examples from various scientific fields. On the other hand, approaches for the characterisation (i.e. size, composition, presence of impurities, etc.) of colloidal solutions containing nanoparticles by the well-established ICP-MS technique are described. In this latter case, the capabilities derived from the on-line coupling of separation techniques such as field-flow fractionation and liquid chromatography with ICP-MS are also assessed. Finally, appealing trends using ICP-MS for bioassays with biomolecules labelled with nanoparticles are delineated.

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Section: Separation Techniques Coupled With Inductively Coupled Plasmmentioning

confidence: 99%

Inorganic mass spectrometry as a tool for characterisation at the nanoscale

et al. 2009

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“…И совершенно не изу чено внутриорганное поведение наночастиц золота размером менее 2 нм, которые стали объек-том нашего внимания [4,7]. Тем более что, по дан-ным ряда работ, при равных условиях (способ вве-дения и время экспозиции) на одни и те же органы наночастицы малых размеров оказывают больший токсический эффект, чем крупные частицы [5,6].…”

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Qualitative analysis of the nephrotoxicity of gold nanoparticles in case of enteral administration

et al. 2017

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The experiments on animals show the different effects of gold nanoparticles. Gold particles of various sizes may have a variety of toxic effects on the tissues, and more damage is often produced by small nanoparticles. In this work histological and ultrastructural changes of renal parenchyma caused by enteric administration of gold nanoparticles of small sizes (2 nm) were studied used different concentrations of colloidal solutions of gold nanoparticles: 10 µg/ml; 50 μg/ml; 100 µg/ml in drinking water within 7, 14 and 28 days. There were 9 groups of animals (non-linear mice weighing 20-25 g) on different dates of the experiment, as well as 3 control groups of mice, respectively, each term of experiment. Histological and ultrastructural changes were detected in the material of all groups of experimental animals compared with control. In general all small focal alterations relate to a small number of vessels, individual profiles of tubules and single cells. Light microscopy analysis of the overall picture of integrity of renal parenchyma showed that the most pronounced changes are observed in the cortex of the organ. Medulla is less affected. It identifies, first of all, microvascular disorders, then the renal tubular epithelium changes and finally, a minor involvement of interstitial elements in the response. Tubules of nephrons compared with the renal corpuscles undergo more changes at all dose levels of exposure and in all periods under study. Signs of dystrophy and necrobiosis often relate to the cell cytoplasm and less of their nuclei. Evidence of microvessel disorders detected in the renal cortex is not dependent on the dose of administered nanoparticles already in the early stages of the experiment. Histological findings as a whole are confirmed by the presence of ultrastructure alterations, that points to the primacy of cell damage.

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“…For example, SEC, coupled to refractive index and multiangle light scattering (MALS) detectors, has been used to characterize polysaccharides present in food samples (Fee et al, 2003;Hokputsa et al, 2004). SEC can also be coupled with a range of detection techniques to characterize NPs, along with the monitoring of the size fractionation (Song et al, 2004;Helfrich et al, 2006).…”

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confidence: 99%

Advanced Analytical Techniques for the Measurement of Nanomaterials in Food and Agricultural Samples: A Review

Bandyopadhyay

Peralta-Videa

Gardea‐Torresdey

2013

Environmental Engineering Science

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Nanotechnology offers substantial prospects for the development of state-of-the-art products and applications for agriculture, water treatment, and food industry. Profuse use of nanoproducts will bring potential benefits to farmers, the food industry, and consumers, equally. However, after end-user applications, these products and residues will find their way into the environment. Therefore, discharged nanomaterials (NMs) need to be identified and quantified to determine their ecotoxicity and the levels of exposure. Detection and characterization of NMs and their residues in the environment, particularly in food and agricultural products, have been limited, as no single technique or method is suitable to identify and quantify NMs. In this review, we have discussed the available literature concerning detection, characterization, and measurement techniques for NMs in food and agricultural matrices, which include chromatography, flow field fractionation, electron microscopy, light scattering, and autofluorescence techniques, among others.

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Size characterisation of Au nanoparticles by ICP-MS coupling techniques

Cited by 97 publications

References 20 publications

Inorganic mass spectrometry as a tool for characterisation at the nanoscale

Inorganic mass spectrometry as a tool for characterisation at the nanoscale

Qualitative analysis of the nephrotoxicity of gold nanoparticles in case of enteral administration

Advanced Analytical Techniques for the Measurement of Nanomaterials in Food and Agricultural Samples: A Review

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