Size-dependent therapeutic efficiency of ²²³Ra-labeled calcium carbonate carriers for internal radionuclide therapy of breast cancer

Abstract

The size of drug carriers strongly affects their biodistribution, tissue penetration, and cellular uptake in vivo.

Encapsulation of a small-molecule drug based on substituted 2-aminothiophenes in calcium carbonate carriers for therapy of melanoma

“…The polymer coating protects CaCO 3 core from complete dissolution in the acidic media. 46 The SEM images demonstrated that MPs and 2-AT@MPs saved their shape and morphology during 12 d of incubation (Fig. 3E and Fig.…”