2024
DOI: 10.1002/jex2.70021
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Size matters: Biomolecular compositions of small and large extracellular vesicles in the urine of glioblastoma patients

Susannah M. Hallal,
Liam A. Sida,
Ágota Tűzesi
et al.

Abstract: The promise of urinary extracellular vesicles (uEVs) in biomarker discovery is emerging. However, the characteristics and compositions of different uEV subpopulations across normal physiological and pathological states require rigorous explication. We recently reported proteomic signatures of small (s)‐uEVs (<200 nm membranous nanoparticles) and described putative biomarkers corresponding to the diagnosis, tumour burden and recurrence of the lethal adult primary brain tumour, glioblastoma. Here, we comprehe… Show more

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