Size-selective silver nanoparticles: future of biomedical devices with enhanced bactericidal properties

Assessment of antibacterial activity of two different sizes of colloidal silver nanoparticle (cAgNPs) against Vibrio harveyi isolated from shrimp Litopenaeus vannamei

“…They found that smaller particles have larger surface area compared to the larger particles. Interestingly, these results agree with those presented by Martínez-Castañón et al (2008); Lago et al (2011);Zhong et al (2013); Ivask et al (2014) and Agnihotri et al (2014). However, it is not wisely only to compare antibacterial efficacy of AgNPs on the basis of size in different studies, since it will depend on various factors, such as shape, surface chemistry, crystallinity, capping agent, dose of AgNPs, bacterial strains and composition of culture media (Hosseinpour Delavar 2014;Nafisi Bahabadi et al 2016).…”

“…Based on Fig. 4, it can be concluded that smaller AgNPs are more effective in killing bacteria than larger particles, probably due to the higher surface area to volume (A/V) ratio in contact with the bacterial cells (Martínez-Castañón et al 2008;Lago et al 2011;Zhong et al 2013;Ivask et al 2014). Therefore, the bactericidal killing properties of AgNPs are size dependent.…”

“…Therefore, to deal with this challenge (bacterial resistance) new therapeutic strategies, such as nanoparticles, can be useful. The use of AgNPs as antibacterial agent is relatively new, and the antibacterial potential of silver nanoparticles has already been proved by many researchers (Morones et al 2005;Kim et al 2007;Sanpui et al 2008;Martínez-Castañón et al 2008;Rai et al 2009;Lago et al 2011;Chudobova et al 2013;Zhong et al 2013;Ivask et al 2014). The aim of present study was to assess the antibacterial effects of two different sizes of cAgNPs against V. harveyi.…”

Antimicrobial technology in orthopedic and spinal implants

“…Silver particles have several known mechanisms of action including binding to thiol groups of enzymes, cell membranes, and nucleic acids, resulting in structural abnormalities, a damaged cell envelope, and inhibition of cell division [39][40][41] . Silver nanoparticles (Figure 3) [42] are typically incorporated into titanium surfaces or polymeric coating to control the release rate and duration of the bioactive silver [11,[43][44][45] . Electrical currents are established when silver nanoparticles (cathode) embedded in a titanium matrix (anode) are exposed to electrolytes [45] -this galvanic coupling can cause changes in bacterial membrane morphology and DNA, leading to cell death [37] .…”

Potentiated Electron Transference in α-Ag2WO4 Microcrystals with Ag Nanofilaments as Microbial Agent

“…26,53 As a general trend, it has been assumed that AgNPs attach to the negatively charged surface of the cell membrane, which causes protein denaturation and subsequent cell death. 54 On the other hand, Panacek et al 29 proposed that these nanoparticles can penetrate inside the bacteria and cause cell damage by interaction with sulfur and phosphorus compounds such as proteins and DNA.…”