Skeletal and dental age discrepancy and occlusal traits in children with growth hormone deficiency and idiopathic short stature

Torlińska-Walkowiak, Natalia; Majewska, Katarzyna Anna; Sowińska, Anna; Kędzia, Andrzej W.; Opydo-Szymaczek, Justyna

doi:10.1007/s00784-022-04566-y

Cited by 3 publications

(1 citation statement)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Before therapy, a delay in the dental maturity and eruption pattern was described, along with a marked delay in bone development and a tendency towards dental crowding. A high risk of dental caries was described in this group of subjects, which decreased following an increase in Vitamin D levels [47,48]. The effects of hormonal treatment, particularly on the dental-oral-craniofacial region, strongly depend on factors such as the age at which treatment starts, its duration, the frequency of administration, and dosages [17].…”

Section: Discussionmentioning

confidence: 81%

Comprehensive Oral Diagnosis and Management for Women with Turner Syndrome

Tallón-Walton,

Sánchez-Molins,

et al. 2024

Diagnostics

View full text Add to dashboard Cite

Turner Syndrome (TS) is a rare genetic disorder that affects females when one of the X chromosomes is partially or completely missing. Due to high genetic and phenotypic variability, TS diagnosis is challenging and is often delayed until adolescence, resulting in poor clinical management. Numerous oral, dental and craniofacial anomalies have been associated with TS, yet a comprehensive description is still lacking. This study addresses this gap through a detailed analysis of oral health and craniofacial characteristics in a cohort of 15 females with TS and their first-degree relatives. Subjects with TS ranged from 3 to 48 years old, none showed evidence of periodontal disease and only the youngest was in mixed dentition. Using the Multifunction System, we identified an aggregation of multiple signs and symptoms in each TS subject, including tooth anomalies (supernumerary molars, agenesis, microdontia, enamel defects, alterations in eruption patterns -advanced and delayed for chronological age-, crowding, rotations and transpositions), malocclusion (class II/1 and II/2) and Class II facial profile, while relatives exhibited fewer manifestations. The early detection of these signs and symptoms is crucial for appropriate referral and the optimal clinical management of TS, especially during the critical period of 9 to 10 years when congenital dental anomalies appear. The use of an established taxonomy to describe these phenotypic features is essential for early detection. Multidisciplinary teams are required to ensure holistic care management in rare diseases like TS.

show abstract

Section: Discussionmentioning

confidence: 81%

Comprehensive Oral Diagnosis and Management for Women with Turner Syndrome

Tallón-Walton,

Sánchez-Molins,

et al. 2024

Diagnostics

View full text Add to dashboard Cite

show abstract

Developmental enamel defects and dental anomalies of number and size in children with growth hormone deficiency

Torlińska-Walkowiak,

Majewska,

Sowińska

et al. 2023

Sci Rep

View full text Add to dashboard Cite

Growth hormone is meaningfully involved in the processes of tooth cells differentiation and tissue formation. The aim of the study was to evaluate the occurrence of dental anomalies: microdontia, macrodontia, hypodontia and developmental defects of enamel (DDE) amongst a group of isolated growth hormone deficient (GHD) patients and healthy children. This cross-sectional study was based on a group of 101 Caucasian children: 33 with GHD (mean age 10.94, SD 2.51) and 68 being healthy, normal height subjects (mean age 10.4, SD 2.38). The dental examination in primary and permanent teeth was carried out by one trained and calibrated dentist, in accordance with the WHO guidelines. It was observed that 33% of GHD patients suffer from dental anomalies (hypodontia, microdontia or macrodontia), the difference between the study group and the control group was statistically significant (33% vs 4%, p < 0.001). Hypodontia and microdontia/macrodontia were the most common problems affecting 18% and 21% of the GHD individuals, respectively. The prevalence of DDE did not differ significantly between GHD group and the control group (58% vs 48%, p > 0.05). As children with GHD present more dental anomalies than their healthy coevals, clinicians should be aware of the possible oral health problems associated with GHD and consider dental screening and management as part of the patient’s overall health care plan.

show abstract

Oral health problems and their management in patients with Down Syndrome—a narrative review

Torlińska-Walkowiak,

Huang,

Wyzga

et al. 2024

Postępy Higieny I Medycyny Doświadczalnej

View full text Add to dashboard Cite

Patients with Down Syndrome (DS) commonly exhibit various anomalies in the masticatory organ and oral cavity. This paper aims to consolidate information regarding oral health challenges faced by individuals with DS, along with strategies employed for their management and care. Our review, conducted via PubMed and Scopus, spanned the period from January 1977 to December 2023. It included original research articles and comprehensive reviews focusing on both pediatric and adult populations. The paper analyzes 71 articles, categorizing them into six sections: oro-facial problems, tooth conditions, dental and skeletal age, dental caries, periodontal diseases, swallowing, masticatory muscles, salivation, behavior management, physical therapy, and early intervention. Understanding oral health issues in individuals with DS is crucial for providing tailored dental care and treatment planning. Regular dental assessments, early intervention strategies such as physiotherapy and behavioral management, and a collaborative approach involving oral health professionals, caregivers, and the individuals themselves are critical to preventing oral health issues and improving overall health and well-being in people with DS.

show abstract

Skeletal and dental age discrepancy and occlusal traits in children with growth hormone deficiency and idiopathic short stature

Cited by 3 publications

References 37 publications

Comprehensive Oral Diagnosis and Management for Women with Turner Syndrome

Comprehensive Oral Diagnosis and Management for Women with Turner Syndrome

Developmental enamel defects and dental anomalies of number and size in children with growth hormone deficiency

Oral health problems and their management in patients with Down Syndrome—a narrative review

Contact Info

Product

Resources

About